(E)-N-(4-chlorobenzylidene)-2,2-dimethoxyethanamine

Base Information

• Chemical Name: (E)-N-(4-chlorobenzylidene)-2,2-dimethoxyethanamine
• CAS No.: 54879-73-1
• Molecular Formula: C11H14ClNO2
• Molecular Weight: 227.691
• Hs Code.: 2922199090
• DSSTox Substance ID: DTXSID30494877
• Mol file: 54879-73-1.mol

Synonyms:54879-73-1;(E)-N-(4-chlorobenzylidene)-2,2-dimethoxyethanamine;DTXSID30494877;(E)-1-(4-Chlorophenyl)-N-(2,2-dimethoxyethyl)methanimine

Chemical Property of (E)-N-(4-chlorobenzylidene)-2,2-dimethoxyethanamine

Chemical Property:

• PSA: 30.82000
• LogP: 2.37780
• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 227.0713064
• Heavy Atom Count: 15
• Complexity: 187

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(CN=CC1=CC=C(C=C1)Cl)OC

Technology Process of (E)-N-(4-chlorobenzylidene)-2,2-dimethoxyethanamine

There total 3 articles about (E)-N-(4-chlorobenzylidene)-2,2-dimethoxyethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-chlorobenzaldehyde (104-88-1) + 2,2-dimethoxyethylamine (22483-09-6) → [1-(4-Chloro-phenyl)-meth-(Z)-ylidene]-(2,2-dimethoxy-ethyl)-amine (54879-73-1)

Guidance literature:

In benzene; Heating;

DOI:10.1021/jm00179a007

Reference yield: 100.0%

4-chlorobenzaldehyde (104-88-1) + 2,2-dimethoxyethylamine (22483-09-6) → N-<(4-chlorophenyl)methylene>-2,2-dimethoxyethanamine (54879-73-1)

Guidance literature:

In toluene; for 1.5h; Heating;

DOI:10.1021/jo01298a038

Reference yield:

→ N-<(4-chlorophenyl)methylene>-2,2-dimethoxyethanamine (54879-73-1)

Guidance literature:

1o, Aminoacetaldehyddimethylacetal (S. 2188);

upstream raw materials:

4-chlorobenzaldehyde

2,2-dimethoxyethylamine

Downstream raw materials:

2-(4-chlorobenzylamino)acetaldehyde dimethyl acetal

N-(4-chlorobenzyl)-N-(2,2-dimethoxyethyl)acetamide

6-chloroisoquinoline

6‐chloro‐1,2,3,4‐tetrahydroisoquinoline