4H-Furo[3,2-b]indole

Base Information

Chemical Name:4H-Furo[3,2-b]indole
CAS No.:55077-51-5
Molecular Formula:C₁₀H₇NO
Molecular Weight:157.172
Hs Code.:
DSSTox Substance ID:DTXSID30495167
Nikkaji Number:J2.510.765I
Wikidata:Q82343129

Synonyms:4H-Furo[3,2-b]indole;55077-51-5;furo[3,2-b]indole;SCHEMBL10411988;DTXSID30495167

Suppliers and Price of 4H-Furo[3,2-b]indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
4H-Furo[3,2-b]indole 97.00%
25G
$ 9110.00

AccelPharmtech
4H-Furo[3,2-b]indole 97.00%
5G
$ 4850.00

AccelPharmtech
4H-Furo[3,2-b]indole 97.00%
1G
$ 2820.00

Total 1 raw suppliers

Chemical Property of 4H-Furo[3,2-b]indole

Chemical Property:

PSA：28.93000
LogP:2.91410
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:157.052763847
Heavy Atom Count:12
Complexity:183

Purity/Quality:: 4H-Furo[3,2-b]indole 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C3=C(N2)C=CO3

Technology Process of 4H-Furo[3,2-b]indole

There total 5 articles about 4H-Furo[3,2-b]indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 55578-83-1
2-(2-azidophenyl)furan

: 55077-51-5
4H-furo[3,2-b]indole

Guidance literature:: In 1,2-dichloro-benzene; at 160 ℃; for 3h;
DOI:10.1021/acs.joc.9b00143

Reference yield: 69.0%

: 55077-51-5
4H-furo[3,2-b]indole

Guidance literature:: With potassium carbonate; triphenylphosphine; In tetrahydrofuran; for 36h; Reflux;

Reference yield:

: 615-36-1
2-bromoaniline

: 55077-51-5
4H-furo[3,2-b]indole

Guidance literature:: Multi-step reaction with 3 steps

1.1: conc. HCl; aq. sodium nitrite / H₂O / 1 h / 0 °C

1.2: 98 percent / sodium azide / H₂O / 1 h / 0 °C

2.1: 42 percent / aq. NaHCO₃ / tetrakis(triphenylphosphine)palladium / 1,2-dimethoxy-ethane / 3.5 h / 100 °C

3.1: 55 percent / 1,2-dichloro-benzene / 4 h / 160 °C

With hydrogenchloride; sodium hydrogencarbonate; sodium nitrite; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; water; 1,2-dichloro-benzene; 2.1: Suzuki-Miyaura cross-coupling reaction;
DOI:10.1016/j.tet.2007.07.068