4-AMino-2-ethoxyphenol

Base Information

• Chemical Name: 4-AMino-2-ethoxyphenol
• CAS No.: 55483-70-0
• Molecular Formula: C8H11NO2
• Molecular Weight: 153.181
• Mol file: 55483-70-0.mol

Synonyms:2-Aethoxy-4-amino-phenol;(3-ethoxy-4-hydroxy-phenyl)-tert-butyl carbamate;4-Amino-brenzcatechin-2-aethylaether;l;4-Amino-2-ethoxypheno;3-Ethoxy-4-hydroxy-anilin;

Chemical Property of 4-AMino-2-ethoxyphenol

Chemical Property:

• Melting Point: 186-188 °C
• Boiling Point: 316.7±27.0 °C(Predicted)
• PKA: 10.36±0.18(Predicted)
• PSA: 55.48000
• Density: 1.172±0.06 g/cm3(Predicted)
• LogP: 1.95430

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-AMino-2-ethoxyphenol

There total 9 articles about 4-AMino-2-ethoxyphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

3-ethoxy-4-hydroxyazobenzene → 3-ethoxy-4-hydroxyaniline (55483-70-0)

Guidance literature:

With hydrated iron(III) oxide; hydrazine hydrate; for 1h; Time; Reflux; Green chemistry;

Reference yield:

2-Ethoxyphenol (94-71-3) → 3-ethoxy-4-hydroxyaniline (55483-70-0)

Guidance literature:

Multi-step reaction with 2 steps

1: alkali

2: hydrogen sulfide; aqueous ammonia

With ammonium hydroxide; hydrogen sulfide;

Reference yield:

4-Nitro-1,2-diethoxybenzene (4992-63-6) → 3-ethoxy-4-hydroxyaniline (55483-70-0)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. KOH / 2-methoxy-ethanol / Heating

2: H₂ / 10 percent Pd/C

With potassium hydroxide; hydrogen; palladium on activated charcoal; In 2-methoxy-ethanol;

DOI:10.1021/jf034367+

upstream raw materials:

N-(m-Ethoxyphenyl)hydroxylamine

3-ethoxy-4-hydroxynitrobenzene

1,2-dihydroxy-4-nitrobenzene

4-Nitro-1,2-diethoxybenzene

Downstream raw materials:

isopropyl 3-ethoxy-4-hydroxycarbanilate

2-acetoxy-3-(3-ethoxy-2-hydroxy-5-isopropoxycarbonylamino-phenylsulfanyl)-propionic acid ethyl ester

3-Ethoxy-4-hydroxy-anilinomethylenmalonsaeurediethylester

2-[(4-decyloxy-3-ethoxy-phenylamino)-methylene]-malonic acid diethyl ester