Acetylphenyldimethylsilane

Base Information

• Chemical Name: Acetylphenyldimethylsilane
• CAS No.: 56583-95-0
• Molecular Formula: C10H14OSi
• Molecular Weight: 178.306
• DSSTox Substance ID: DTXSID70452956
• Nikkaji Number: J227.555D
• Wikidata: Q82273872
• Mol file: 56583-95-0.mol

Synonyms:Acetylphenyldimethylsilane;56583-95-0;acetyldimethylphenylsilane;DTXSID70452956

Chemical Property of Acetylphenyldimethylsilane

Chemical Property:

• PSA: 17.07000
• LogP: 1.73020
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 178.081391600
• Heavy Atom Count: 12
• Complexity: 169

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(=O)[Si](C)(C)C1=CC=CC=C1

Technology Process of Acetylphenyldimethylsilane

There total 13 articles about Acetylphenyldimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(1-methoxyvinyl)dimethyl(phenyl)silane (79678-02-7) → 1-(dimethyl(phenyl)silyl)ethanone (56583-95-0)

Guidance literature:

With hydrogenchloride; In acetone; at 20 ℃; for 1.16667h;

DOI:10.1016/0022-328X(93)80452-H

Reference yield: 93.0%

ethyl vinyl ether (109-92-2,25104-37-4) + phenyldimethylsilyl chloride (768-33-2) → 1-(dimethyl(phenyl)silyl)ethanone (56583-95-0)

Guidance literature:

ethyl vinyl ether; With tert.-butyl lithium; In tetrahydrofuran; n-heptane; at -78 - 0 ℃; for 0.833333h;

phenyldimethylsilyl chloride; In tetrahydrofuran; n-heptane; at -78 - 20 ℃; for 15h;

With toluene-4-sulfonic acid; In water; acetonitrile; at 20 ℃; for 1h;

DOI:10.1002/adsc.201700162

Reference yield: 92.0%

dimethyl(2-methyl-1,3-dithiacyclohexan-2-yl)phenylsilan (58309-61-8) → 1-(dimethyl(phenyl)silyl)ethanone (56583-95-0)

Guidance literature:

With cadmium(II) carbonate; water; mercury dichloride; In water; acetone; benzene; for 1h; Heating;

DOI:10.1016/0022-328X(86)80492-2

upstream raw materials:

dimethyl(2-methyl-1,3-dithiacyclohexan-2-yl)phenylsilan

acetic acid methyl ester

dimethyl(phenyl)silyllithium

N,N-dimethyl acetamide

Downstream raw materials:

1-Phenylethanol

ethyl (E)-3-(dimethyl(phenyl)silyl)-2-butenoate

2-(dimethyl(phenyl)silyl)-5,5-dimethylhex-3-yn-2-ol

7-(tert-butyldimethylsilyloxy)-2-(dimethyl(phenyl)silyl)hept-3-yn-2-ol