1-(2-Bromoethoxy)-2-iodobenzene

Base Information

• Chemical Name: 1-(2-Bromoethoxy)-2-iodobenzene
• CAS No.: 57056-94-7
• Molecular Formula: C8H8BrIO
• Molecular Weight: 326.959
• DSSTox Substance ID: DTXSID10565352
• Nikkaji Number: J708.405F
• Wikidata: Q82450405
• Mol file: 57056-94-7.mol

Synonyms:1-(2-Bromoethoxy)-2-iodobenzene;57056-94-7;Benzene, 1-(2-bromoethoxy)-2-iodo-;SCHEMBL23630245;DTXSID10565352;A933983;A1-61745

Chemical Property of 1-(2-Bromoethoxy)-2-iodobenzene

Chemical Property:

• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 325.88033
• Heavy Atom Count: 11
• Complexity: 110

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)OCCBr)I

Technology Process of 1-(2-Bromoethoxy)-2-iodobenzene

There total 2 articles about 1-(2-Bromoethoxy)-2-iodobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2-Iodophenol (533-58-4) + ethylene dibromide (106-93-4) → 1-(2-bromoethoxy)-2-iodobenzene (57056-94-7)

Guidance literature:

With potassium carbonate; In acetonitrile; at 80 ℃; for 6h;

DOI:10.1155/2017/6175315

Reference yield:

2-Iodophenol (533-58-4) + ethylene dibromide (106-93-4) → 1-(2-bromoethoxy)-2-iodobenzene (57056-94-7) + 1,2-bis-(2-iodo-phenoxy)-ethane

Guidance literature:

With ethanol; sodium ethanolate;

DOI:10.1021/ja01258a054

Reference yield: 98.0%

1-(2-bromoethoxy)-2-iodobenzene (57056-94-7) → 1-iodo-2-(vinyloxy)benzene (57056-90-3)

Guidance literature:

With potassium tert-butylate; In dimethyl sulfoxide; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1021/acs.orglett.0c03876

upstream raw materials:

2-Iodophenol

ethylene dibromide

Downstream raw materials:

1-iodo-2-(vinyloxy)benzene

2.3-dihydrobenzofuran

1-(3-methylbut-1-ynyl)-2-vinyloxybenzene

3-(4-methoxyphenyl)-2-methylbenzofuran