Benzoic acid, 2-amino-5-methoxy-4-[3-(1-piperidinyl)propoxy]-, methyl ester

Base Information

Chemical Name:Benzoic acid, 2-amino-5-methoxy-4-[3-(1-piperidinyl)propoxy]-, methyl ester
CAS No.:574738-68-4
Molecular Formula:C17H26N2O4
Molecular Weight:322.404
Hs Code.:
Mol file:574738-68-4.mol

Synonyms:2-Amino-5-methoxy-4-(3-piperidin-1-yl-propoxy)-benzoic acid methyl ester;methyl 5-methoxy-4-(3-piperidinopropoxy)anthranilate;methyl 2-amino-4-piperidinopropoxy-5-methoxybenzoate;methyl 2-amino-5-methoxy-4-(3-piperidin-1-yl-propoxy)benzoate;

Suppliers and Price of Benzoic acid, 2-amino-5-methoxy-4-[3-(1-piperidinyl)propoxy]-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of Benzoic acid, 2-amino-5-methoxy-4-[3-(1-piperidinyl)propoxy]-, methyl ester

Chemical Property:

PSA：74.02000
LogP:2.83790

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of Benzoic acid, 2-amino-5-methoxy-4-[3-(1-piperidinyl)propoxy]-, methyl ester

There total 7 articles about Benzoic acid, 2-amino-5-methoxy-4-[3-(1-piperidinyl)propoxy]-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 927173-22-6
methyl 5-methoxy-2-nitro-4-(3-(piperidin-1-yl)propoxy)benzoate

: 574738-68-4
methyl 2-amino-5-methoxy-4-(3-(piperidin-1-yl)propoxy)benzoate

Guidance literature:: With hydrogenchloride; tin(II) chloride dihdyrate; at 20 ℃;
DOI:10.1016/j.bmcl.2016.08.060

Reference yield:

: 3943-74-6
4-hydroxy-3-methoxybenzoic acid methyl ester

: 574738-68-4
methyl 2-amino-5-methoxy-4-(3-(piperidin-1-yl)propoxy)benzoate

Guidance literature:: Multi-step reaction with 4 steps

1: potassium carbonate; tetrabutylammonium iodide / acetone / 2 h / Heating

2: acetic acid; nitric acid / 3 h / 20 - 50 °C

3: 86 percent / potassium carbonate; tetrabutylammonium iodide; sodium iodide / acetonitrile / 3 h / Heating

4: hydrogen / PtO₂*H₂O / methanol / 48 h / 20 °C / 2068.59 Torr

With hydrogen; nitric acid; tetra-(n-butyl)ammonium iodide; potassium carbonate; acetic acid; sodium iodide; platinum(IV) oxide; In methanol; acetone; acetonitrile;
DOI:10.3390/11040286

Reference yield:

: 214470-57-2
methyl 4-(3-chloropropoxy)-5-methoxy-2-nitrobenzoate

: 574738-68-4
methyl 2-amino-5-methoxy-4-(3-(piperidin-1-yl)propoxy)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / potassium carbonate; tetrabutylammonium iodide; sodium iodide / acetonitrile / 3 h / Heating

2: hydrogen / PtO₂*H₂O / methanol / 48 h / 20 °C / 2068.59 Torr

With hydrogen; tetra-(n-butyl)ammonium iodide; potassium carbonate; sodium iodide; platinum(IV) oxide; In methanol; acetonitrile;
DOI:10.3390/11040286