tert-Butyl glycidyl ether

Base Information

• Chemical Name: tert-Butyl glycidyl ether
• CAS No.: 7665-72-7
• Deprecated CAS: 126753-05-7
• Molecular Formula: C7H14 O2
• Molecular Weight: 130.187
• Hs Code.: 2910900090
• European Community (EC) Number: 231-640-0
• UN Number: 3271
• UNII: 35F8X83D0G
• DSSTox Substance ID: DTXSID4024692
• Nikkaji Number: J65.719K
• Wikidata: Q27256462
• ChEMBL ID: CHEMBL1569413
• Mol file: 7665-72-7.mol

Synonyms:tert-butyl glycidyl ether

Chemical Property of tert-Butyl glycidyl ether

Chemical Property:

• Vapor Pressure: 4.56mmHg at 25°C
• Melting Point: -70oC
• Refractive Index: n20/D 1.417(lit.)
• Boiling Point: 152°Cat760mmHg
• Flash Point: 43.3°C
• PSA: 21.76000
• Density: 0.944g/cm³
• LogP: 1.20030
• Water Solubility.: 90.3g/L at 20℃
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 130.099379685
• Heavy Atom Count: 9
• Complexity: 93.6
• Transport DOT Label: Flammable Liquid

Purity/Quality:

98% ^*data from raw suppliers

tert-Butyl Glycidyl Ether ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 10-19-22-36-43
• Safety Statements: 16-26-36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Plastics & Rubber -> Glycidyl Ethers
• Canonical SMILES: CC(C)(C)OCC1CO1

Technology Process of tert-Butyl glycidyl ether

There total 6 articles about tert-Butyl glycidyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

1-chloro-3-tert-butoxy-2-propanol (22576-65-4) → t-butyl glycidyl ether (7665-72-7)

Guidance literature:

With sodium hydroxide; at 5 ℃; for 1h;

DOI:10.1021/ja00341a045

Reference yield:

allyl tert-butyl ether (1471-04-1) → t-butyl glycidyl ether (7665-72-7)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 45 ℃; for 48h;

Reference yield:

1,2-Epoxy-3-bromopropane (3132-64-7,82584-73-4) + tert-butyl alcohol (75-65-0) → t-butyl glycidyl ether (7665-72-7)

Guidance literature:

With boron trifluoride; In diethyl ether; at 50 - 55 ℃;

upstream raw materials:

epichlorohydrin

tert-butyl alcohol

allyl tert-butyl ether

1-chloro-3-tert-butoxy-2-propanol

Downstream raw materials:

1-tert-Butoxy-3-diethylamino-propan-2-ol

(S)-2-(tert-butoxymethyl)oxirane

(R)-tert-butyl glycidyl ether

1-chloro-3-tert-butoxy-2-propanol

Refernces

• 1、 Zaitsev, L. M.,Korotkii, Yu. V.,Krasavtsev, I. I.,Lozinskii, M. O.. "SYNTHESIS AND UTEROSTIMULATING ACTIVITY OF DERIVATIVES OF 1-DIALKYLAMINO-3-ALKOXY-2-PROPANOL". . p. 492 - 495. Retrieved 2007/10/02.
• 2、 Allakhverdiev, M. A.,Farzaliev, V. M.,Khalilova, A. Z.,Ibragimov, N. Yu.,Sultanov, Yu. M.,Cherkasova, E. M.. "REACTION OF tert-BUTOXYMETHYL-SUBSTITUTED THIIRANE WITH VARIOUS AMINES". . p. 2054 - 2058. Retrieved 2007/10/02.