2-Phenyl-2H-[1,3]dioxolo[4,5-F]indazole

Base Information

Chemical Name:2-Phenyl-2H-[1,3]dioxolo[4,5-F]indazole
CAS No.:57695-86-0
Molecular Formula:C14H10N2O2
Molecular Weight:238.246
Hs Code.:
DSSTox Substance ID:DTXSID10482712
Nikkaji Number:J596.334F
Wikidata:Q82319332

Synonyms:2-PHENYL-2H-[1,3]DIOXOLO[4,5-F]INDAZOLE;57695-86-0;2H-[1,3]Dioxolo[4,5-f]indazole, 2-phenyl-;DTXSID10482712

Suppliers and Price of 2-Phenyl-2H-[1,3]dioxolo[4,5-F]indazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Phenyl-2H-[1,3]dioxolo[4,5-f]indazole 97%
1g
$ 623.00

Alichem
2-Phenyl-2h-[1,3]dioxolo[4,5-f]indazole
1g
$ 654.16

Total 3 raw suppliers

Chemical Property of 2-Phenyl-2H-[1,3]dioxolo[4,5-F]indazole

Chemical Property:

PSA：36.28000
LogP:2.75420
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:238.074227566
Heavy Atom Count:18
Complexity:306

Purity/Quality:

99% ^*data from raw suppliers

2-Phenyl-2H-[1,3]dioxolo[4,5-f]indazole 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1OC2=CC3=CN(N=C3C=C2O1)C4=CC=CC=C4

Technology Process of 2-Phenyl-2H-[1,3]dioxolo[4,5-F]indazole

There total 10 articles about 2-Phenyl-2H-[1,3]dioxolo[4,5-F]indazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 5434-47-9
5-bromo-6-bromomethylbenzo[1,3]dioxole

: 100-63-0
phenylhydrazine

: 57695-86-0
5,6-(methylenedioxy)-2-phenyl-2H-indazole

Guidance literature:: 5-bromo-6-bromomethylbenzo[1,3]dioxole; phenylhydrazine; With caesium carbonate; In dimethyl sulfoxide; at 20 ℃; for 3h; Inert atmosphere; Sealed tube;

With caesium carbonate; palladium dichloride; tri tert-butylphosphoniumtetrafluoroborate; In dimethyl sulfoxide; at 120 ℃; for 18h; regioselective reaction; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.joc.0c01923

Reference yield: 51.0%

: 138306-34-0
[1-(6-Nitro-benzo[1,3]dioxol-5-yl)-meth-(E)-ylidene]-phenyl-amine

: 57695-86-0
5,6-(methylenedioxy)-2-phenyl-2H-indazole

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; carbon monoxide; tin(ll) chloride; In tetrahydrofuran; at 100 ℃; for 16h; under 14710.2 Torr;
DOI:10.1039/c39910001466

Reference yield:

: 95547-07-2
CH₂O₂C₆H₂(CHNC₆H₅)Br

: 57695-86-0
5,6-(methylenedioxy)-2-phenyl-2H-indazole

Guidance literature:: With copper(l) iodide; sodium azide; N,N,N,N,-tetramethylethylenediamine; In dimethyl sulfoxide; at 120 ℃; for 24h;
DOI:10.1021/acs.orglett.8b00920