8-Nitro[1,2,4]triazolo[4,3-a]pyridine

Base Information

Chemical Name:8-Nitro[1,2,4]triazolo[4,3-a]pyridine
CAS No.:31040-09-2
Molecular Formula:C6H4 N4 O2
Molecular Weight:164.123
Hs Code.:2933990090
NSC Number:116469
DSSTox Substance ID:DTXSID80297517
Nikkaji Number:J101.539G
Wikidata:Q82038643
Mol file:31040-09-2.mol

Synonyms:8-nitro-[1,2,4]triazolo[4,3-a]pyridine;31040-09-2;8-Nitro[1,2,4]triazolo[4,3-a]pyridine;1,2,4-Triazolo[4,3-a]pyridine, 8-nitro-;NSC116469;s-Triazolo[4,3-a]pyridine, 8-nitro-;8-Nitro-1,2,4-triazolo[4,3-a]pyridine;s-Triazolo[4, 8-nitro-;DTXSID80297517;VKNXTGMZHIZTOZ-UHFFFAOYSA-N;NSC-116469;8-Nitro[1,2,4]triazolo[4,3-a]pyridine #

Suppliers and Price of 8-Nitro[1,2,4]triazolo[4,3-a]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemcia Scientific
8-Nitro-[1,2,4]triazolo[4,3-a]pyridine 95%
1 G
$ 240.00

American Custom Chemicals Corporation
8-NITRO-1,2,4-TRIAZOLO[4,3-A]PYRIDINE 95.00%
5MG
$ 495.96

Total 3 raw suppliers

Chemical Property of 8-Nitro[1,2,4]triazolo[4,3-a]pyridine

Chemical Property:

PKA:0.13±0.50(Predicted)
PSA：76.01000
Density:1.68g/cm³
LogP:1.16070
XLogP3:1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:164.03342538
Heavy Atom Count:12
Complexity:193

Purity/Quality:

99% ^*data from raw suppliers

8-Nitro-[1,2,4]triazolo[4,3-a]pyridine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN2C=NN=C2C(=C1)[N+](=O)[O-]

Technology Process of 8-Nitro[1,2,4]triazolo[4,3-a]pyridine

There total 1 articles about 8-Nitro[1,2,4]triazolo[4,3-a]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 64-18-6
formic acid

: 15367-16-5
2-Hydrazino-3-nitropyridine

: 31040-09-2
8-nitro-1,2,4-triazolo[4,3-a]pyridine

Guidance literature:: at 150 ℃; for 2.5h; Inert atmosphere;
DOI:10.1021/jm401356t

Reference yield:

: 31040-09-2
8-nitro-1,2,4-triazolo[4,3-a]pyridine

: 1340879-45-9
N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)-2-(4-methoxyphenyl)acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydrogencarbonate / 1.5 h / 20 °C / Inert atmosphere

2: hydrogen; palladium 10% on activated carbon / ethanol / 1.5 h / 50 °C / 1034.32 Torr / Inert atmosphere

3: triethylamine / dichloromethane / 16 h / 20 °C / Inert atmosphere

With palladium 10% on activated carbon; hydrogen; sodium hydrogencarbonate; triethylamine; In ethanol; dichloromethane;
DOI:10.1021/jm401356t

Reference yield:

: 31040-09-2
8-nitro-1,2,4-triazolo[4,3-a]pyridine

: 1569870-48-9
N-(4-methoxyphenethyl)-[1,2,4]triazolo[1,5-a]pyridin-8-amine

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydrogencarbonate / 1.5 h / 20 °C / Inert atmosphere

2: hydrogen; palladium 10% on activated carbon / ethanol / 1.5 h / 50 °C / 1034.32 Torr / Inert atmosphere

3: triethylamine / dichloromethane / 16 h / 20 °C / Inert atmosphere

4: lithium aluminium tetrahydride / dichloromethane / 16 h / 0 °C / Inert atmosphere

With lithium aluminium tetrahydride; palladium 10% on activated carbon; hydrogen; sodium hydrogencarbonate; triethylamine; In ethanol; dichloromethane;
DOI:10.1021/jm401356t