(4Z)-4-(2-fluorobenzylidene)-2-phenyl-1,3-oxazol-5(4H)-one

Base Information

Chemical Name:(4Z)-4-(2-fluorobenzylidene)-2-phenyl-1,3-oxazol-5(4H)-one
CAS No.:397-60-4
Molecular Formula:C₁₆H₁₀FNO₂
Molecular Weight:267.259
Hs Code.:
European Community (EC) Number:206-906-4
NSC Number:74501
Mol file:397-60-4.mol

Synonyms:4-(2-Fluorobenzylidene)-2-phenyloxazol-5(4H)-one;397-60-4;(4Z)-4-(2-fluorobenzylidene)-2-phenyl-1,3-oxazol-5(4H)-one;NSC74501;5(4H)-Oxazolone, 4-((2-fluorophenyl)methylene)-2-phenyl-;Cl-6177;NSC-74501;STK028251;AKOS000516127;SR-01000417456;SR-01000417456-1;(z)-2-phenyl-4-(2-fluorobenzylidene)-2-oxazolin-5-one;4-(2-fluorobenzylidene)-2-phenyl-1,3-oxazol-5(4h)-one

Suppliers and Price of (4Z)-4-(2-fluorobenzylidene)-2-phenyl-1,3-oxazol-5(4H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of (4Z)-4-(2-fluorobenzylidene)-2-phenyl-1,3-oxazol-5(4H)-one

Chemical Property:

Vapor Pressure:3.76E-06mmHg at 25°C
Boiling Point:385.6°Cat760mmHg
Flash Point:187°C
PSA：38.66000
Density:1.23g/cm³
LogP:2.60580
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:267.06955672
Heavy Atom Count:20
Complexity:438

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NC(=CC3=CC=CC=C3F)C(=O)O2
Isomeric SMILES:C1=CC=C(C=C1)C2=N/C(=C\C3=CC=CC=C3F)/C(=O)O2

Technology Process of (4Z)-4-(2-fluorobenzylidene)-2-phenyl-1,3-oxazol-5(4H)-one

There total 8 articles about (4Z)-4-(2-fluorobenzylidene)-2-phenyl-1,3-oxazol-5(4H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 495-69-2,140480-84-8,21251-67-2,91787-63-2,66407-11-2
Hippuric Acid

: 446-52-6
2-Fluorobenzaldehyde

: 143051-42-7,397-60-4
(Z)-4-(2-fluorobenzylidene)-2-phenyloxazol-5(4H)-one

Guidance literature:: With lemon juice; at 25 - 30 ℃; Irradiation;
DOI:10.2174/1386207322666191024105150

Reference yield: 70.0%

: C₁₆H₁₀FN₃O₃

: 397-60-4
4-[1-(2-Fluoro-phenyl)-meth-(Z)-ylidene]-2-phenyl-4H-oxazol-5-one

Guidance literature:: With 1,1,3,3-Tetramethyldisiloxane; copper(II) bis(trifluoromethanesulfonate); triphenylphosphine; In toluene; Reflux;
DOI:10.1021/acscatal.6b00165

Reference yield: 70.0%

: C₉H₆FN₃O₂

: 98-88-4
benzoyl chloride

: 143051-42-7,397-60-4
(Z)-4-(2-fluorobenzylidene)-2-phenyloxazol-5(4H)-one

Guidance literature:: With 1,1,3,3-Tetramethyldisiloxane; copper(II) bis(trifluoromethanesulfonate); triethylamine; triphenylphosphine; In toluene; Reflux;
DOI:10.1021/acscatal.6b00165