alpha-L-Glu-L-Asp

Base Information

• Chemical Name: alpha-L-Glu-L-Asp
• CAS No.: 3918-84-1
• Molecular Formula: C9H14 N2 O7
• Molecular Weight: 262.219
• Hs Code.: 2924199090
• NSC Number: 186905
• DSSTox Substance ID: DTXSID20959965
• Mol file: 3918-84-1.mol

Synonyms:NSC-186905;.alpha.-L-Glu-L-Asp;SCHEMBL1674757;DTXSID20959965;FYYSIASRLDJUNP-UHFFFAOYSA-N;.alpha.-L-glutamyl-L-aspartic acid;NSC186905;AKOS020224611;FT-0771858;N-(2-Amino-4-carboxy-1-hydroxybutylidene)aspartic acid

Chemical Property of alpha-L-Glu-L-Asp

Chemical Property:

• Vapor Pressure: 2.33E-16mmHg at 25°C
• Boiling Point: 608.2°Cat760mmHg
• Flash Point: 321.6°C
• PSA: 167.02000
• Density: 1.53g/cm³
• LogP: -0.68620
• Storage Temp.: -15°C
• XLogP3: -4.6
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 8
• Exact Mass: 262.08010079
• Heavy Atom Count: 18
• Complexity: 355

Purity/Quality:

99%+, ^*data from raw suppliers

Glu-Asp-OH ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CC(=O)O)C(C(=O)NC(CC(=O)O)C(=O)O)N

Technology Process of alpha-L-Glu-L-Asp

There total 4 articles about alpha-L-Glu-L-Asp which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(N-benzyloxycarbonyl-L-α-glutamyl)-L-aspartic acid (97707-08-9) → L-Glu-L-Asp-OH (3918-84-1)

Guidance literature:

With methanol; palladium; Hydrogenation;

DOI:10.1039/jr9500001954

Reference yield:

N-(N-benzyloxycarbonyl-L-α-glutamyl)-L-aspartic acid diethyl ester (100658-82-0) → L-Glu-L-Asp-OH (3918-84-1)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous NaOH

2: palladium; aqueous methanol / Hydrogenation

With methanol; sodium hydroxide; palladium;

DOI:10.1039/jr9500001954

Reference yield:

L-Aspartic acid (56-84-8,25608-40-6,27881-03-4,32505-46-7,52526-39-3) + L-glutamic acid (56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6) → L-Glu-L-Asp-OH (3918-84-1)

Guidance literature:

Multistep reaction;

upstream raw materials:

N-(N-benzyloxycarbonyl-L-α-glutamyl)-L-aspartic acid

L-Aspartic acid

L-glutamic acid

N-(N-benzyloxycarbonyl-L-α-glutamyl)-L-aspartic acid diethyl ester

Downstream raw materials:

L-Aspartic acid

L-glutamic acid

Refernces

• 1、 -. "Cell adhesion and extracellular matrix proteins". . . Retrieved 2008/06/13.
• 2、 Tamura, Masahiro,Nakatsuka, Tohru,Tada, Makoto,Kawasaki, Yoshihiro,Kikuchi, Eiichi,Okai, Hideo. "The Relationship between Taste and Primary Structure of "Delicious Peptide" (Lys-Gly-Asp-Glu-Glu-Ser-Leu-Ala) from Beef Soup". . p. 319 - 326. Retrieved 2007/10/02.