4-Methyl-3-{[tri(propan-2-yl)silyl]oxy}aniline

Base Information

Chemical Name:4-Methyl-3-{[tri(propan-2-yl)silyl]oxy}aniline
CAS No.:582322-76-7
Molecular Formula:C16H29NOSi
Molecular Weight:279.498
Hs Code.:
DSSTox Substance ID:DTXSID90591856
Wikidata:Q82485724

Synonyms:582322-76-7;4-Methyl-3-((triisopropylsilyl)oxy)aniline;4-Methyl-3-{[tri(propan-2-yl)silyl]oxy}aniline;SCHEMBL6022524;DTXSID90591856

Suppliers and Price of 4-Methyl-3-{[tri(propan-2-yl)silyl]oxy}aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-Methyl-3-{[tri(propan-2-yl)silyl]oxy}aniline

Chemical Property:

Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:279.201841083
Heavy Atom Count:19
Complexity:256

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=C(C=C1)N)O[Si](C(C)C)(C(C)C)C(C)C

Technology Process of 4-Methyl-3-{[tri(propan-2-yl)silyl]oxy}aniline

There total 4 articles about 4-Methyl-3-{[tri(propan-2-yl)silyl]oxy}aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1643447-97-5
4-methyl-3-(triisopropylsilyloxy)nitrobenzene

: 582322-76-7
4-methyl-3-(triisopropylsilyloxy)aniline

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; dichloromethane; at 20 ℃; for 72h; under 3000.3 Torr;
DOI:10.1002/chem.201403143

Reference yield: 90.0%

: 13154-24-0
triisopropylsilyl chloride

: 5428-54-6
2-methyl-5-nitrophenol

: 582322-76-7
4-methyl-3-(triisopropylsilyloxy)aniline

Guidance literature:: triisopropylsilyl chloride; 2-methyl-5-nitrophenol; With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃; for 21h; Inert atmosphere;

With iron; acetic acid; at 40 ℃; for 4h;
DOI:10.1002/chem.201604002

Reference yield:

: 13154-24-0
triisopropylsilyl chloride

: 582322-76-7
4-methyl-3-(triisopropylsilyloxy)aniline

Guidance literature:: Multi-step reaction with 2 steps

1: 1H-imidazole / N,N-dimethyl-formamide / 17.5 h / 20 °C / Inert atmosphere

2: acetic acid; iron / 3 h / 60 °C / Inert atmosphere

With 1H-imidazole; iron; acetic acid; In N,N-dimethyl-formamide;
DOI:10.1039/c4ob00367e