2,4,6-Tris(diethylamino)-1,3,5-triazine

Base Information

• Chemical Name: 2,4,6-Tris(diethylamino)-1,3,5-triazine
• CAS No.: 2827-49-8
• Molecular Formula: C15H30 N6
• Molecular Weight: 294.443
• Hs Code.: 2933699090
• European Community (EC) Number: 220-590-5
• NSC Number: 37756
• UNII: KL2T8ELG5S
• DSSTox Substance ID: DTXSID6075221
• Nikkaji Number: J306.762I
• Wikidata: Q82003234
• ChEMBL ID: CHEMBL395999
• Mol file: 2827-49-8.mol

Synonyms:2,4,6-Tris(diethylamino)-1,3,5-triazine;2827-49-8;2-N,2-N,4-N,4-N,6-N,6-N-hexaethyl-1,3,5-triazine-2,4,6-triamine;AI3-51033;1,3,5-Triazine-2,4,6-triamine, N,N,N',N',N'',N''-hexaethyl-;EINECS 220-590-5;NSC-37756;N2,N2,N4,N4,N6,N6-hexaethyl-1,3,5-triazine-2,4,6-triamine;NSC37756;HEXAETHYLMELAMINE;KL2T8ELG5S;Oprea1_509596;CHEMBL395999;SCHEMBL2741119;DTXSID6075221;C15H30N6;NSC 37756;2,4,6-Tris(diethylamino)-s-triazine;C15-H30-N6;E87600;SR-01000201489;SR-01000201489-1;1,3,5-Triazine-2,4,6-triamine, N2,N2,N4,N4,N6,N6-hexaethyl-;N,N,N',N',N'',N''-Hexaethyl-1,3,5-triazine-2,4,6-triamine;N,N,N',N',N'',N''-HEXAETHYL-[1,3,5]TRIAZINE-2,4,6-TRIAMINE

Chemical Property of 2,4,6-Tris(diethylamino)-1,3,5-triazine

Chemical Property:

• Vapor Pressure: 2.39E-07mmHg at 25°C
• Boiling Point: 422.5°Cat760mmHg
• Flash Point: 209.3°C
• PSA: 48.39000
• Density: 1.043g/cm³
• LogP: 2.41020
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 9
• Exact Mass: 294.25319498
• Heavy Atom Count: 21
• Complexity: 208

Purity/Quality:

99% ^*data from raw suppliers

N,N,N',N',N'',N''-HEXAETHYL-[1,3,5]TRIAZINE-2,4,6-TRIAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CC)C1=NC(=NC(=N1)N(CC)CC)N(CC)CC

Technology Process of 2,4,6-Tris(diethylamino)-1,3,5-triazine

There total 7 articles about 2,4,6-Tris(diethylamino)-1,3,5-triazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1,3,5-trichloro-2,4,6-triazine (108-77-0) + triethylamine (121-44-8) → N2,N2,N4,N4,N6,N6-hexaethyl-1,3,5-triazine-2,4,6-triamine (2827-49-8)

Guidance literature:

In dichloromethane; at 0 ℃;

DOI:10.1016/j.tet.2009.03.017

Reference yield: 92.0%

1,3,5-trichloro-2,4,6-triazine (108-77-0) + diethylamine (109-89-7) → N2,N2,N4,N4,N6,N6-hexaethyl-1,3,5-triazine-2,4,6-triamine (2827-49-8)

Guidance literature:

HY zeolite; In water; at 180 ℃; for 0.0833333h; microwave irradiation;

DOI:10.1016/j.bmcl.2007.04.007

Reference yield: 60.0%

N-(chloroformyl)-N',N'-diethyl-N-methylurea (84014-81-3) → N2,N2,N4,N4,N6,N6-hexaethyl-1,3,5-triazine-2,4,6-triamine (2827-49-8)

Guidance literature:

at 150 - 220 ℃; for 0.333333h;

upstream raw materials:

1,3,5-trichloro-2,4,6-triazine

diethylamine

2-chloro-4,6-bis(diethylamino)-1,3,5-triazine

N-(chloroformyl)-N',N'-diethyl-N-methylurea

Downstream raw materials:

diethylamine

isocyanuric acid

Refernces

• 1、 Kolesinska, Beata,Kaminski, Zbigniew J.. "The umpolung of substituent effect in nucleophilic aromatic substitution. A new approach to the synthesis of N,N-disubstituted melamines (triazine triskelions) under mild reaction conditions". experimental part. p. 3573 - 3576. Retrieved 2009/09/08.
• 2、 Reddy, N. Dastagiri,Elias, Anil J.,Vij, Ashwani. "N-Dealkylation of aliphatic tertiary amines and diamines with cyanuric chloride: Crystal structure of 2,4-dichloro-6-(N-ethyl-N-isopropyl amino)-s-triazine". . p. 2033 - 2055. Retrieved 2007/10/03.