N-(6-Bromothiazolo[5,4-b]pyridin-2-yl)benzamide

Base Information

Chemical Name:N-(6-Bromothiazolo[5,4-b]pyridin-2-yl)benzamide
CAS No.:588730-01-2
Molecular Formula:C13H8BrN3OS
Molecular Weight:334.196
Hs Code.:2934999090
DSSTox Substance ID:DTXSID60451478
Wikidata:Q82271526
Mol file:588730-01-2.mol

Synonyms:588730-01-2;N-(6-Bromothiazolo[5,4-b]pyridin-2-yl)benzamide;N-(6-Bromo-[1,3]thiazolo[5,4-b]pyridin-2-yl)benzamide;SCHEMBL12997560;DTXSID60451478;POTYDBWSMIMCHL-UHFFFAOYSA-N;BS-29212

Suppliers and Price of N-(6-Bromothiazolo[5,4-b]pyridin-2-yl)benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
N-(6-Bromothiazolo[5,4-b]pyridin-2-yl)benzamide 95+%
5g
$ 923.00

Total 3 raw suppliers

Chemical Property of N-(6-Bromothiazolo[5,4-b]pyridin-2-yl)benzamide

Chemical Property:

PSA：83.12000
Density:1.718g/cm3
LogP:3.77910
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:332.95715
Heavy Atom Count:19
Complexity:338

Purity/Quality:

99% ^*data from raw suppliers

N-(6-Bromothiazolo[5,4-b]pyridin-2-yl)benzamide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)NC2=NC3=C(S2)N=CC(=C3)Br

Technology Process of N-(6-Bromothiazolo[5,4-b]pyridin-2-yl)benzamide

There total 4 articles about N-(6-Bromothiazolo[5,4-b]pyridin-2-yl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: N-(5-bromo-2-fluoropyridin-3-ylcarbamothioyl)benzamide

: 588730-01-2
N-(6-bromo-thiazolo[5,4-b]pyridine-2-yl)-benzamide

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; water; at 60 ℃; for 16h;

Reference yield: 78.0%

: 588729-97-9
N-(6-bromo[1,3]thiazolo[4,5-b]pyridin-2-yl)benzamide

: 588730-01-2
N-(6-bromo-thiazolo[5,4-b]pyridine-2-yl)-benzamide

Guidance literature:: With sodium methylate; In 1-methyl-pyrrolidin-2-one; at 120 ℃; for 4h;
DOI:10.1002/jhet.5570400210

Reference yield:

: 98-88-4
benzoyl chloride

: 588730-01-2
N-(6-bromo-thiazolo[5,4-b]pyridine-2-yl)-benzamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: acetone / 0.08 h / Heating

1.2: 100 percent / acetone / 1 h / Heating

2.1: 67 percent / NaOMe / 1-methyl-pyrrolidin-2-one / 4 h / 120 °C

3.1: 78 percent / NaOMe / 1-methyl-pyrrolidin-2-one / 4 h / 120 °C

With sodium methylate; In 1-methyl-pyrrolidin-2-one; acetone;
DOI:10.1002/jhet.5570400210