3-(tritylamino)propanoic Acid

Base Information

Chemical Name:3-(tritylamino)propanoic Acid
CAS No.:58995-30-5
Molecular Formula:C22H21NO2
Molecular Weight:331.414
Hs Code.:
European Community (EC) Number:653-222-0
DSSTox Substance ID:DTXSID70408716
Nikkaji Number:J2.383.217H
Wikidata:Q82214292

Synonyms:3-(tritylamino)propanoic Acid;58995-30-5;3-(TRITYL-AMINO)-PROPIONIC ACID;3-(tritylamino)propionic acid;SCHEMBL4211757;DTXSID70408716;DRBJRRIAZMJBOC-UHFFFAOYSA-N;AKOS024334042

Suppliers and Price of 3-(tritylamino)propanoic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 3-(tritylamino)propanoic Acid

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:331.157228913
Heavy Atom Count:25
Complexity:359

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)NCCC(=O)O

Technology Process of 3-(tritylamino)propanoic Acid

There total 2 articles about 3-(tritylamino)propanoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.5%

: 35737-10-1
N-Fmoc-β-alanine

: 76-83-5
trityl chloride

: 58995-30-5
N-trityl-β-alanine

Guidance literature:: N-Fmoc-β-alanine; 2-chlorotrityl resin; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 2h;

With piperidine; In N,N-dimethyl-formamide; at 20 ℃; for 0.333333h;

trityl chloride; Further stages;
DOI:10.1002/anie.201606065

Reference yield:

: 58995-30-5
N-trityl-β-alanine

Guidance literature:: N-Trityl-β-alanin-methylester, methanol. KOH, Siedetemp.;

Reference yield: 88.0%

: 58995-30-5
N-trityl-β-alanine

: N,N-dibenzyl-4-aminobutanamide

: 334513-21-2
N,N-dibenzyl-4-(3-tritylamino)propanamidobutanamide

Guidance literature:: N,N-dibenzyl-4-aminobutanamide; With triethylamine; In chloroform; at 0 ℃; for 0.25h;

N-trityl-β-alanine; With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; In chloroform; at 0 - 20 ℃; for 1h;
DOI:10.1016/j.bmc.2015.04.069