2-Bromo-4-trifluoromethyl-8-quinolinecarboxylic Acid

Base Information

Chemical Name:2-Bromo-4-trifluoromethyl-8-quinolinecarboxylic Acid
CAS No.:590372-23-9
Molecular Formula:C11H5BrF3NO2
Molecular Weight:320.06200
Hs Code.:2933499090
Mol file:590372-23-9.mol

Synonyms:PC9242;2-bromo-4-trifluoromethyl-8-quinolinecarboxylic acid;

Suppliers and Price of 2-Bromo-4-trifluoromethyl-8-quinolinecarboxylic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Bromo-4-(trifluoromethyl)quinoline-8-carboxylicacid 95+%
1g
$ 762.00

Chemenu
2-bromo-4-(trifluoromethyl)quinoline-8-carboxylicacid 95%
1g
$ 720.00

American Custom Chemicals Corporation
2-BROMO-4-(TRIFLUOROMETHYL)QUINOLINE-8-CARBOXYLIC ACID 95.00%
5MG
$ 500.42

Alichem
2-Bromo-4-(trifluoromethyl)quinoline-8-carboxylicacid
1g
$ 632.40

Total 5 raw suppliers

Chemical Property of 2-Bromo-4-trifluoromethyl-8-quinolinecarboxylic Acid

Chemical Property:

PSA：50.19000
LogP:3.71430

Purity/Quality:

98% ^*data from raw suppliers

2-Bromo-4-(trifluoromethyl)quinoline-8-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Bromo-4-trifluoromethyl-8-quinolinecarboxylic Acid

There total 2 articles about 2-Bromo-4-trifluoromethyl-8-quinolinecarboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 124-38-9,18923-20-1
carbon dioxide

: 590372-08-0
2-bromo-8-iodo-4-(trifluoromethyl)quinoline

: 590372-23-9
2-bromo-4-trifluoromethyl-8-quinolinecarboxylic acid

Guidance literature:: With n-butyllithium; In hexane; toluene; at -75 ℃; for 0.25h;
DOI:10.1002/ejoc.200390215

Reference yield:

: 590372-06-8
8-iodo-4-(trifluoromethyl)quinolin-2(1H)-one

: 590372-23-9
2-bromo-4-trifluoromethyl-8-quinolinecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / phosphorus oxybromide / 2 h / 120 °C

2: 81 percent / butyllithium / hexane; toluene / 0.25 h / -75 °C

With n-butyllithium; phosphorus(V) oxybromide; In hexane; toluene;
DOI:10.1002/ejoc.200390215