1,2,4-Triazolo(4,3-b)pyridazine, 8-methyl-6-(4-morpholinyl)-

Base Information

Chemical Name:1,2,4-Triazolo(4,3-b)pyridazine, 8-methyl-6-(4-morpholinyl)-
CAS No.:56383-06-3
Molecular Formula:C₁₀H₁₃N₅O
Molecular Weight:219.246
Hs Code.:
DSSTox Substance ID:DTXSID00204940
Wikidata:Q83078428

Synonyms:1,2,4-Triazolo(4,3-b)pyridazine, 8-methyl-6-(4-morpholinyl)-;56383-06-3;8-Methyl-6-morpholino-s-triazolo(4,3-b)pyridazine;8-Methyl-6-(4-morpholinyl)-1,2,4-triazolo(4,3-b)pyridazine;8-methyl-6-morpholino-s-triazolo[4,3-b]pyridazine;SCHEMBL11537619;DTXSID00204940;RTZZIZHPNUMMKR-UHFFFAOYSA-N;AKOS024353745;LS-156693

Suppliers and Price of 1,2,4-Triazolo(4,3-b)pyridazine, 8-methyl-6-(4-morpholinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,2,4-Triazolo(4,3-b)pyridazine, 8-methyl-6-(4-morpholinyl)-

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.46g/cm³
XLogP3:0.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:219.11201006
Heavy Atom Count:16
Complexity:245

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NN2C1=NN=C2)N3CCOCC3

Technology Process of 1,2,4-Triazolo(4,3-b)pyridazine, 8-methyl-6-(4-morpholinyl)-

There total 4 articles about 1,2,4-Triazolo(4,3-b)pyridazine, 8-methyl-6-(4-morpholinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 110-91-8,99108-56-2
morpholine

: 58826-40-7
6-chloro-8-methyl-1,2,4-triazolo[4,3-b]-pyridazine

: 56383-06-3
8-methyl-6-morpholino[1,2,4]triazolo[4,3-b]pyridazine

Guidance literature:: In ethanol; for 8h; Heating;
DOI:10.1135/cccc20051372

Reference yield:

: 19064-64-3
3,6-dichloro-4-methylpyridazine

: 56383-06-3
8-methyl-6-morpholino[1,2,4]triazolo[4,3-b]pyridazine

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrazine hydrate / ethanol / 24 h / 20 °C

1.2: 1 h / Heating

2.1: 65 percent / ethanol / 8 h / Heating

With hydrazine hydrate; In ethanol;
DOI:10.1135/cccc20051372

Reference yield:

: 66530-55-0
6-chloro-3-hydrazino-4-methylpyridazine

: 56383-06-3
8-methyl-6-morpholino[1,2,4]triazolo[4,3-b]pyridazine

Guidance literature:: Multi-step reaction with 2 steps

1: 62 percent / 1 h / Heating

2: 65 percent / ethanol / 8 h / Heating

In ethanol;
DOI:10.1135/cccc20051372