Phenol, 4-[[(4-methoxyphenyl)methylene]amino]-

Base Information

• Chemical Name: Phenol, 4-[[(4-methoxyphenyl)methylene]amino]-
• CAS No.: 3230-39-5
• Molecular Formula: C₁₄H₁₃NO₂
• Molecular Weight: 227.263
• Hs Code.: 2925290090
• European Community (EC) Number: 221-768-5
• NSC Number: 112115
• UNII: CY6TQC6XHV
• DSSTox Substance ID: DTXSID1062918
• Nikkaji Number: J208.701D
• ChEMBL ID: CHEMBL67238
• Mol file: 3230-39-5.mol

Synonyms:3230-39-5;N-(4-Methoxybenzylidene)-4-hydroxyaniline;Phenol, 4-[[(4-methoxyphenyl)methylene]amino]-;p-Methoxybenzylidene p-aminophenol;4-[(4-methoxyphenyl)methylideneamino]phenol;4-[(4-methoxybenzylidene)amino]phenol;p-(p-Methoxybenzylideneamino)phenol;4-(4-Methoxybenzylidene)-4-hydroxyaniline;p-((p-Methoxybenzylidene)amino)phenol;4-((4-Methoxybenzylidene)amino)phenol;CHEMBL67238;Phenol, p-((p-methoxybenzylidene)amino)-;Phenol, 4-(((4-methoxyphenyl)methylene)amino)-;4-(4-Methoxybenzylideneamino)Phenol;EINECS 221-768-5;p-[(p-Methoxybenzylidene)amino]phenol;NSC 112115;NSC-112115;AI3-52023;Phenol, p-[(p-methoxybenzylidene)amino]-;NSC112115;CY6TQC6XHV;4-(p-Anisalamino)phenol;Maybridge1_002362;CBDivE_002035;DivK1c_001114;SCHEMBL2911723;N-(p-Anisal)-4-hydroxyaniline;DTXSID1062918;HMS548D08;N-(p-Anisylidene)-4-hydroxyaniline;BDBM50429684;MFCD00037176;STK047364;AKOS000490993;4'-Methoxybenzylidene-4-hydroxyaniline;CDS1_000074;AS-64996;CD 00977;4-Hydroxy-N-(4-methoxybenzylidene)aniline;4-[1-Aza-2-(4-methoxyphenyl)vinyl]phenol;4-[[(4-Methoxyphenyl)methylene]amino]phenol;CS-0314914;FT-0676031;M0605;4-[(E)-(4-methoxyphenyl)methyleneamino]phenol;T72291;4-((4-METHOXY-BENZYLIDENE)-AMINO)-PHENOL;4-[(E)-[(4-Methoxyphenyl)methylene]amino]phenol;AN-329/05191041;4-[(E)-[(4-methoxyphenyl)methylidene]amino]phenol;4-{[(E)-(4-methoxyphenyl)methylidene]amino}phenol;4-([(E)-(4-Methoxyphenyl)methylidene]amino)phenol #;Phenol, 4-[(E)-[(4-methoxyphenyl)methylene]amino]-

Chemical Property of Phenol, 4-[[(4-methoxyphenyl)methylene]amino]-

Chemical Property:

• Vapor Pressure: 2.53E-07mmHg at 25°C
• Melting Point: 189 °C
• Boiling Point: 410.5°C at 760 mmHg
• Flash Point: 202°C
• PSA: 41.82000
• Density: 1.08g/cm³
• LogP: 3.15140
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 227.094628657
• Heavy Atom Count: 17
• Complexity: 239

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-(4-Methoxybenzylidene)-4-hydroxyaniline >98.0%(T) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C=NC2=CC=C(C=C2)O

Technology Process of Phenol, 4-[[(4-methoxyphenyl)methylene]amino]-

There total 4 articles about Phenol, 4-[[(4-methoxyphenyl)methylene]amino]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.9%

4-amino-phenol (123-30-8) + 4-methoxy-benzaldehyde (123-11-5) → 4-[(4-methoxybenzylidene)amino]phenol (67097-24-9,3230-39-5)

Guidance literature:

In ethanol; at 80 ℃; for 2h; Reflux; Inert atmosphere;

DOI:10.1016/j.ejmech.2016.04.029

Reference yield:

(4-hydroxy-anilino)-(4-methoxy-phenyl)-methanesulfonic acid → 4-[(4-methoxybenzylidene)amino]phenol (67097-24-9,3230-39-5)

Guidance literature:

at 188 ℃;

Reference yield:

→ 4-[(4-methoxybenzylidene)amino]phenol (67097-24-9,3230-39-5)

Guidance literature:

p-H3CO-C6H4-CHO, p-H2N-C6H4-OH;

upstream raw materials:

4-amino-phenol

4-methoxy-benzaldehyde

Downstream raw materials:

4-(4-Methoxy-benzylamino)-phenol

N-(p-Methoxybenzyliden)-p'-heptanoyloxyanilin

N-(p-dimethyl-t-butylsiloxybenzylidene)-p-methoxyaniline.