3'-(2-Hydroxy-3-morpholinopropoxy)acetophenone

Base Information

Chemical Name:3'-(2-Hydroxy-3-morpholinopropoxy)acetophenone
CAS No.:63990-82-9
Molecular Formula:C15H21 N O4
Molecular Weight:279.3315
Hs Code.:

Synonyms:1-(3-acetylphenoxy)-3-(morpholin-4-yl)-2-propanol;GPV 384

Suppliers and Price of 3'-(2-Hydroxy-3-morpholinopropoxy)acetophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3'-((2-HYDROXY-3-MORPHOLINO)PROPOXY)ACETOPHENONE 95.00%
5MG
$ 500.61

Total 1 raw suppliers

Chemical Property of 3'-(2-Hydroxy-3-morpholinopropoxy)acetophenone

Chemical Property:

Vapor Pressure:2.04E-09mmHg at 25°C
Boiling Point:464.2°Cat760mmHg
Flash Point:234.5°C
PSA：59.00000
Density:1.161g/cm³
LogP:0.89900

Purity/Quality:: 3'-((2-HYDROXY-3-MORPHOLINO)PROPOXY)ACETOPHENONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3'-(2-Hydroxy-3-morpholinopropoxy)acetophenone

There total 5 articles about 3'-(2-Hydroxy-3-morpholinopropoxy)acetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 110-91-8,99108-56-2
morpholine

: 42865-03-2
1-[3-(2,3-epoxy-propoxy)-phenyl]-ethanone

: 63990-82-9
1-[3-(2-hydroxy-3-morpholin-4-yl-propoxy)-phenyl]-ethanone

Guidance literature:: In ethanol; for 8h; Heating;

Reference yield:

: 121-71-1
3-Hydroxyacetophenone

: 63990-82-9
1-[3-(2-hydroxy-3-morpholin-4-yl-propoxy)-phenyl]-ethanone

Guidance literature:: Multi-step reaction with 2 steps

1.1: (CF₃)3COH / chiral polymer-supported Co(salen) complex / 6 h / 4 - 25 °C

1.2: KOH / diethyl ether / 3 h / 25 °C

2.1: Yb(OTf)3 / CH₂Cl₂ / 16 h / 25 °C

With 1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)propan-2-ol; ytterbium(III) triflate; chiral polymer-supported Co(salen) complex; In dichloromethane;
DOI:10.1021/ol990920q