1-[3-(Oxiran-2-ylmethoxy)phenyl]ethanone

Base Information

• Chemical Name: 1-[3-(Oxiran-2-ylmethoxy)phenyl]ethanone
• CAS No.: 42865-03-2
• Molecular Formula: C₁₁H₁₂O₃
• Molecular Weight: 192.214
• Hs Code.: 2914509090
• DSSTox Substance ID: DTXSID60395500
• Mol file: 42865-03-2.mol

Synonyms:42865-03-2;1-[3-(oxiran-2-ylmethoxy)phenyl]ethanone;1-(3-(Oxiran-2-ylmethoxy)phenyl)ethanone;1-[3-(oxiran-2-ylmethoxy)phenyl]ethan-1-one;1-{3-[(Oxiran-2-yl)methoxy]phenyl}ethan-1-one;SCHEMBL6915703;DTXSID60395500;CS-0221751;EN300-09947;Z104492434

Chemical Property of 1-[3-(Oxiran-2-ylmethoxy)phenyl]ethanone

Chemical Property:

• Vapor Pressure: 0.000628mmHg at 25°C
• Melting Point: 43 °C
• Boiling Point: 309.7°Cat760mmHg
• Flash Point: 132.1°C
• PSA: 38.83000
• Density: 1.162g/cm³
• LogP: 1.66680
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 192.078644241
• Heavy Atom Count: 14
• Complexity: 215

Purity/Quality:

90% ^*data from raw suppliers

1-[3-(oxiran-2-ylmethoxy)phenyl]ethan-1-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)C1=CC(=CC=C1)OCC2CO2

Technology Process of 1-[3-(Oxiran-2-ylmethoxy)phenyl]ethanone

There total 2 articles about 1-[3-(Oxiran-2-ylmethoxy)phenyl]ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-Hydroxyacetophenone (121-71-1) + epichlorohydrin (106-89-8,24969-06-0,13403-37-7) → 1-[3-(2,3-epoxy-propoxy)-phenyl]-ethanone (42865-03-2)

Guidance literature:

With sodium hydroxide;

Reference yield:

sodium 3-acetylphenoxide (3019-87-2) + epichlorohydrin (106-89-8,24969-06-0,13403-37-7) → 1-[3-(2,3-epoxy-propoxy)-phenyl]-ethanone (42865-03-2)

Guidance literature:

In ethanol; for 6h; Ambient temperature;

Reference yield: 86.0%

morpholine (110-91-8,99108-56-2) + 1-[3-(2,3-epoxy-propoxy)-phenyl]-ethanone (42865-03-2) → 1-[3-(2-hydroxy-3-morpholin-4-yl-propoxy)-phenyl]-ethanone (63990-82-9)

Guidance literature:

In ethanol; for 8h; Heating;

upstream raw materials:

3-Hydroxyacetophenone

epichlorohydrin

sodium 3-acetylphenoxide

Downstream raw materials:

1-[3-(2-hydroxy-3-morpholin-4-yl-propoxy)-phenyl]-ethanone