N-Benzyl-6-(methylsulfanyl)-1H-pyrazolo[3,4-D]pyrimidin-4-amine

Base Information

Chemical Name:N-Benzyl-6-(methylsulfanyl)-1H-pyrazolo[3,4-D]pyrimidin-4-amine
CAS No.:594865-02-8
Molecular Formula:C13H13N5S
Molecular Weight:271.346
Hs Code.:
DSSTox Substance ID:DTXSID50472490
Wikidata:Q82301456

Synonyms:594865-02-8;N-Benzyl-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-amine;N-BENZYL-6-(METHYLSULFANYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE;DTXSID50472490

Suppliers and Price of N-Benzyl-6-(methylsulfanyl)-1H-pyrazolo[3,4-D]pyrimidin-4-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N-Benzyl-6-(methylsulfanyl)-1H-pyrazolo[3,4-D]pyrimidin-4-amine

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:271.08916661
Heavy Atom Count:19
Complexity:284

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CSC1=NC2=C(C=NN2)C(=N1)NCC3=CC=CC=C3

Technology Process of N-Benzyl-6-(methylsulfanyl)-1H-pyrazolo[3,4-D]pyrimidin-4-amine

There total 3 articles about N-Benzyl-6-(methylsulfanyl)-1H-pyrazolo[3,4-D]pyrimidin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 85426-79-5
4-chloro-6-methylmercapto-1H-pyrazolo[3,4-d]pyrimidine

: 100-46-9
benzylamine

: 594865-02-8
benzyl-(6-methylsulfanyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-amine

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In butan-1-ol; at 50 ℃; for 24h;
DOI:10.1016/S0223-5234(03)00065-5

Reference yield:

: 5334-26-9
4-hydroxy-6-methylmercapto-1H-pyrazolo[3,4-d]pyrimidine

: 594865-02-8
benzyl-(6-methylsulfanyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / POCl₃; PhNMe₂

2: 95 percent / iPr₂NEt / butan-1-ol / 24 h / 50 °C

With N,N-dimethyl-aniline; N-ethyl-N,N-diisopropylamine; trichlorophosphate; In butan-1-ol;
DOI:10.1016/S0223-5234(03)00065-5

Reference yield:

: 24521-76-4
4-hydroxy-6-mercapto-1H-pyrazolo[3,4-d]pyrimidine

: 594865-02-8
benzyl-(6-methylsulfanyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 99 percent / NaOH

2: 92 percent / POCl₃; PhNMe₂

3: 95 percent / iPr₂NEt / butan-1-ol / 24 h / 50 °C

With sodium hydroxide; N,N-dimethyl-aniline; N-ethyl-N,N-diisopropylamine; trichlorophosphate; In butan-1-ol;
DOI:10.1016/S0223-5234(03)00065-5