1-[(2-Methylpropyl)amino]-3-phenoxypropan-2-ol

Base Information

Chemical Name:1-[(2-Methylpropyl)amino]-3-phenoxypropan-2-ol
CAS No.:39631-75-9
Molecular Formula:C13H21NO2
Molecular Weight:223.3113
Hs Code.:
NSC Number:36013
DSSTox Substance ID:DTXSID60284162
ChEMBL ID:CHEMBL31811

Synonyms:39631-75-9;CHEMBL31811;1-[(2-methylpropyl)amino]-3-phenoxypropan-2-ol;NSC36013;DTXSID60284162;BDBM50404784;NSC-36013;AKOS008928713

Suppliers and Price of 1-[(2-Methylpropyl)amino]-3-phenoxypropan-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-[(2-Methylpropyl)amino]-3-phenoxypropan-2-ol

Chemical Property:

Vapor Pressure:1.1E-05mmHg at 25°C
Boiling Point:356.1°Cat760mmHg
Flash Point:169.1°C
Density:1.017g/cm³
XLogP3:2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:223.157228913
Heavy Atom Count:16
Complexity:167

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CNCC(COC1=CC=CC=C1)O

Technology Process of 1-[(2-Methylpropyl)amino]-3-phenoxypropan-2-ol

There total 2 articles about 1-[(2-Methylpropyl)amino]-3-phenoxypropan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 122-60-1,71031-02-2
Phenyl glycidyl ether

: 78-81-9
isobutylamine

: 39631-75-9
1-(isobutylamino)-3-phenoxypropan-2-ol

Guidance literature:: Phenyl glycidyl ether; isobutylamine; In N,N-dimethyl-formamide; at 60 ℃; for 12h; Sealed tube;

With water; In N,N-dimethyl-formamide; at 60 ℃; for 12h; regioselective reaction; Sealed tube;
DOI:10.1055/s-0036-1588356

Reference yield:

: 108-95-2,27073-41-2
phenol

: 39631-75-9
1-(isobutylamino)-3-phenoxypropan-2-ol

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / acetone / 24 h / Inert atmosphere; Reflux

2.1: N,N-dimethyl-formamide / 12 h / 60 °C / Sealed tube

2.2: 12 h / 60 °C / Sealed tube

With potassium carbonate; In N,N-dimethyl-formamide; acetone;
DOI:10.1055/s-0036-1588356