2-Amino-1,1-dimethylethylisopropylamine

Base Information

• Chemical Name: 2-Amino-1,1-dimethylethylisopropylamine
• CAS No.: 5448-29-3
• Molecular Formula: C7H18 N2
• Molecular Weight: 130.233
• Hs Code.: 2921290000
• European Community (EC) Number: 226-671-1
• NSC Number: 17712
• UNII: XY2CCA73SX
• DSSTox Substance ID: DTXSID10969654
• Nikkaji Number: J210.493H
• Wikidata: Q27157628
• Mol file: 5448-29-3.mol

Synonyms:5448-29-3;2-Amino-1,1-dimethylethylisopropylamine;N1-Isopropyl-2-methylpropane-1,2-diamine;1,2-Propanediamine, 2-methyl-N1-(1-methylethyl)-;(2-amino-2-methylpropyl)(propan-2-yl)amine;2-methyl-1-N-propan-2-ylpropane-1,2-diamine;XY2CCA73SX;N(1)-isopropyl-2-methylpropan-1,2-diamine;EINECS 226-671-1;NSC 17712;NSC-17712;AI3-28056;N1-Isopropyl-2-methyl-1,2-propanediamine;N1-isopropyl-2-methyl-propane-1,2-diamine;NSC17712;starbld0048595;UNII-XY2CCA73SX;SCHEMBL4527622;CHEBI:84265;DTXSID10969654;AKOS010515717;2-Methyl-N-isopropyl-1,2-propanediamine;1-[N-Isopropyl]-2.2-dimethylathylendiamin;N-1-isopropyl-2-methylpropane-1,2-diamine;N1 -isopropyl-2-methyl-1,2-propanediamine;Nl -isopropyl-2-methyl-1,2-propanediamine;CS-0001053;2-AMINO-1-ISOPROPYLAMINO-2-METHYLPROPANE;EN300-1260359;2-methyl-N(1)-(propan-2-yl)propane-1,2-diamine;N1-ISOPROPYL-1,2-DIAMINO-2-METHYLPROPANE;1,2-Propanediamine,2-methyl-N1-(1-methylethyl)-;2-Methyl-N~1~-(propan-2-yl)propane-1,2-diamine;1,2-Propanediamine, 2-methyl-N(1)-(1-methylethyl)-;Q27157628;2-METHYL-N1-(1-METHYLETHYL)-1,2-PROPANEDIAMINE;F8882-4516

Chemical Property of 2-Amino-1,1-dimethylethylisopropylamine

Chemical Property:

• Vapor Pressure: 1.7mmHg at 25°C
• Boiling Point: 167.5°Cat760mmHg
• Flash Point: 90.6°C
• PSA: 38.05000
• Density: 0.829g/cm³
• LogP: 1.81290
• XLogP3: 0.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 130.146998583
• Heavy Atom Count: 9
• Complexity: 77

Purity/Quality:

99% ^*data from raw suppliers

2-METHYL-N1-(1-METHYLETHYL)-1,2-PROPANEDIAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)NCC(C)(C)N

Technology Process of 2-Amino-1,1-dimethylethylisopropylamine

There total 6 articles about 2-Amino-1,1-dimethylethylisopropylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

[2-Azido-2-methyl-prop-(E)-ylidene]-isopropyl-amine → N-(2-aminoisobutyl)isopropylamine (5448-29-3)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 2h; Heating;

DOI:10.1055/s-1993-25989

Reference yield:

isopropyl-(β-nitro-isobutyl)-amine (89850-87-3) → N-(2-aminoisobutyl)isopropylamine (5448-29-3)

Guidance literature:

With methanol; nickel; at 30 - 50 ℃; under 25742.8 Torr; Hydrogenation;

Reference yield:

[2-Chloro-2-methyl-prop-(E)-ylidene]-isopropyl-amine (62134-67-2) → N-(2-aminoisobutyl)isopropylamine (5448-29-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / NaN₃ / dimethylsulfoxide / 16 h / 50 °C

2: 86 percent / LiAlH₄ / diethyl ether / 2 h / Heating

With lithium aluminium tetrahydride; sodium azide; In diethyl ether; dimethyl sulfoxide;

DOI:10.1055/s-1993-25989

upstream raw materials:

isopropyl-(β-nitro-isobutyl)-amine

2,2,5,5-tetramethylimidazolidine-4-thione

formaldehyd

2-nitropropane

Downstream raw materials:

2-[2]furyl-1-isopropyl-4,4-dimethyl-imidazolidine

5,5-Dimethyl-1-isopropyl-2,3-diketopiperazin

1-isopropyl-4,4-dimethyl-4,5-dihydro-1H-imidazole

1-isopropyl-4,4-dimethyl-2-phenyl-imidazolidine