(1E)-1-[1-(4-methylphenyl)ethylidene]-2-phenylhydrazine

Base Information

• Chemical Name: (1E)-1-[1-(4-methylphenyl)ethylidene]-2-phenylhydrazine
• CAS No.: 54779-81-6
• Molecular Formula: C15H16N2
• Molecular Weight: 224.305
• NSC Number: 68562
• Mol file: 54779-81-6.mol

Synonyms:NSC68562;54779-81-6;(1E)-1-[1-(4-methylphenyl)ethylidene]-2-phenylhydrazine;NSC-68562;STK215774;AKOS002288965

Chemical Property of (1E)-1-[1-(4-methylphenyl)ethylidene]-2-phenylhydrazine

Chemical Property:

• Vapor Pressure: 6.81E-05mmHg at 25°C
• Boiling Point: 343.9°Cat760mmHg
• Flash Point: 161.8°C
• Density: 0.99g/cm³
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 224.131348519
• Heavy Atom Count: 17
• Complexity: 246

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)C(=NNC2=CC=CC=C2)C
• Isomeric SMILES: CC1=CC=C(C=C1)/C(=N/NC2=CC=CC=C2)/C

Technology Process of (1E)-1-[1-(4-methylphenyl)ethylidene]-2-phenylhydrazine

There total 4 articles about (1E)-1-[1-(4-methylphenyl)ethylidene]-2-phenylhydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

phenylhydrazine hydrochloride (59-88-1) + para-methylacetophenone (122-00-9) → 4-methylacetophenone phenylhydrazone (54779-81-6)

Guidance literature:

With sodium acetate; In water; at 20 ℃;

DOI:10.1016/j.bmc.2018.12.031

Reference yield: 95.0%

para-methylacetophenone (122-00-9) + phenylhydrazine (100-63-0) → 4-methylacetophenone phenylhydrazone (54779-81-6)

Guidance literature:

With oxaline; In neat (no solvent); at 25 - 30 ℃; for 0.0833333h; Reagent/catalyst; Solvent; Time; Green chemistry;

DOI:10.1016/j.molliq.2013.11.036

Reference yield: 95.0%

phenyl hydrazine hydrochloride + para-methylacetophenone (122-00-9) → 4-methylacetophenone phenylhydrazone (54779-81-6)

Guidance literature:

With sodium acetate; In water; at 20 ℃; for 3.5h;

DOI:10.1016/j.ejmech.2019.03.026

upstream raw materials:

para-methylacetophenone

phenylhydrazine

phenylhydrazine hydrochloride

4-n-methylphenylacetylene

Downstream raw materials:

2-(4-methylphenyl)-1H-indole

5-phenacyl-1-phenyl-3-(4-tolyl)pyrazole

1-phenyl-3-(p-tolyl)-1H-pyrazole-4-carbaldehyde

1-phenyl-3-(4-methylphenyl)-4,5-dihydropyrazol-5-one