2-bromo-N,N-dimethylprop-2-en-1-amine

Base Information

• Chemical Name: 2-bromo-N,N-dimethylprop-2-en-1-amine
• CAS No.: 14326-14-8
• Molecular Formula: C5H10 Br N
• Molecular Weight: 164.045
• NSC Number: 172856
• DSSTox Substance ID: DTXSID80305944
• Nikkaji Number: J133.728I
• Wikidata: Q82052775
• Mol file: 14326-14-8.mol

Synonyms:2-bromo-N,N-dimethylprop-2-en-1-amine;14326-14-8;2-Bromo-N,N-dimethyl-2-propen-1-amine;NSC172856;2-Propen-1-amine, 2-bromo-N,N-dimethyl-;SCHEMBL326263;DTXSID80305944;ZECQWMIJWDURLX-UHFFFAOYSA-N;NSC-172856;N-(2-Bromo-2-propenyl)-N,N-dimethylamine #

Chemical Property of 2-bromo-N,N-dimethylprop-2-en-1-amine

Chemical Property:

• Vapor Pressure: 9.09mmHg at 25°C
• Boiling Point: 131.9°Cat760mmHg
• Flash Point: 33.6°C
• Density: 1.297g/cm³
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 162.99966
• Heavy Atom Count: 7
• Complexity: 68.5

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CC(=C)Br

Technology Process of 2-bromo-N,N-dimethylprop-2-en-1-amine

There total 1 articles about 2-bromo-N,N-dimethylprop-2-en-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

dimethyl amine (124-40-3) + 2-bromoallyl bromide (513-31-5) → 2-bromo-N,N-dimethyl-allylamine (14326-14-8)

Guidance literature:

In benzene; 20 deg C, then Rt 3 h, then 60 deg C, 30 min;

DOI:10.1002/hlca.19820650142

Reference yield:

2-bromo-N,N-dimethyl-allylamine (14326-14-8) → N,N-Dimethylpropargylamin (7223-38-3)

Guidance literature:

With ammonia; sodium amide;

Reference yield:

2-bromo-N,N-dimethyl-allylamine (14326-14-8) → dimethyl 4-diemthylaminomethyl-4-cyclohexene-trans-1,2-dicarboxylate (133733-58-1,133733-59-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) Mg / 2) Ni(dppp)Cl₂ / 1) THF, 2) THF, 17h, RT

2: 92 percent / CHCl₃ / 20 h / Heating

With magnesium; 1,3-bis[(diphenylphosphino)propane]dichloronickel(II); In chloroform;

DOI:10.1246/bcsj.64.1051

upstream raw materials:

dimethyl amine

2-bromoallyl bromide

Downstream raw materials:

N,N-Dimethylpropargylamin

[2-(Diphenyl-hydrazonomethyl)-allyl]-dimethyl-amine

2-Dimethylaminomethyl-1,1-diphenyl-prop-2-en-1-ol

3-Dimethylaminomethyl-1,2-diphenyl-but-3-en-2-ol