1-Butanone, 2-methyl-1,2-diphenyl-, (R)-

Base Information

• Chemical Name: 1-Butanone, 2-methyl-1,2-diphenyl-, (R)-
• CAS No.: 60366-01-0
• Molecular Formula: C17H18O
• Molecular Weight: 238.329
• Mol file: 60366-01-0.mol

Synonyms:

Chemical Property of 1-Butanone, 2-methyl-1,2-diphenyl-, (R)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Butanone, 2-methyl-1,2-diphenyl-, (R)-

There total 14 articles about 1-Butanone, 2-methyl-1,2-diphenyl-, (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

(R)-2-methyl-1,2-diphenylbut-3-en-1-one (1413934-94-7) → (R)-2-methyl-1,2-diphenylbut-3-en-1-one (60366-01-0)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In ethyl acetate; at 20 ℃; for 5h; stereospecific reaction;

DOI:10.1021/ja306602g

Reference yield: 80.0%

(2R)-2-methyl-1,2-diphenylbutan-1-ol (1190868-78-0) → (R)-2-methyl-1,2-diphenylbut-3-en-1-one (60366-01-0)

Guidance literature:

With pyridinium chlorochromate; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1002/anie.200901900

Reference yield: 78.0%

C15H23O4P + phenylmagnesium bromide (100-58-3) → (S)-2-methyl-1,2-diphenyl-butan-1-one (60366-01-0,83289-87-6,94802-58-1)

Guidance literature:

C₁₅H₂₃O₄P; phenylmagnesium bromide; In tetrahydrofuran; at -78 ℃;

With ammonium chloride; In water;

With sodium hydrogencarbonate; In water;

DOI:10.1021/acscatal.8b03591

upstream raw materials:

phenylmagnesium bromide

diphenyl cadmium

(-)-(2R)-2-Methyl-2-phenylbutanoyl chloride

(2R)-2-methyl-1,2-diphenylbutan-1-ol

Downstream raw materials:

(1R,2S)-2-methyl-1,2-diphenyl-butan-1-ol

(1S,2S)-2-methyl-1,2-diphenyl-butan-1-ol

(2Ξ,3S)-3-methyl-2,3-diphenyl-pentan-2-ol

(1R,2R)-2-methyl-1,2-diphenyl-butan-1-ol