Milameline

Base Information

Chemical Name:Milameline
CAS No.:139886-32-1
Molecular Formula:C₈H₁₄N₂O
Molecular Weight:154.212
Hs Code.:
European Community (EC) Number:692-558-2
UNII:R9X77R42FN
DSSTox Substance ID:DTXSID401028867
Wikipedia:Milameline
NCI Thesaurus Code:C132273
Pharos Ligand ID:BM4S8FL1RA53
ChEMBL ID:CHEMBL151938
Mol file:139886-32-1.mol

Synonyms:1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxaldehyde O-methyloxime monohydrochloride;CI 979;CI 979, (E)-isomer HCl;CI-979;CI979;milameline

Suppliers and Price of Milameline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Milameline hydrochloride
10mg
$ 403.00

Tocris
Milamelinehydrochloride ≥99%(HPLC)
10
$ 163.00

Tocris
Milamelinehydrochloride ≥99%(HPLC)
50
$ 683.00

American Custom Chemicals Corporation
MILAMELINE 95.00%
50MG
$ 1102.40

American Custom Chemicals Corporation
MILAMELINE 95.00%
10MG
$ 673.08

Total 9 raw suppliers

Chemical Property of Milameline

Chemical Property:

Vapor Pressure:0.109mmHg at 25°C
Boiling Point:221.1°Cat760mmHg
Flash Point:87.5°C
PSA：24.83000
Density:1g/cm³
LogP:0.81840
Storage Temp.:Desiccate at -20°C
XLogP3:0.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:154.110613074
Heavy Atom Count:11
Complexity:175

Purity/Quality:

98%min ^*data from raw suppliers

Milameline hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCC=C(C1)C=NOC
Isomeric SMILES:CN1CCC=C(C1)/C=N/OC
Uses Milameline is a muscarinic receptor agonist.

Technology Process of Milameline

There total 2 articles about Milameline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 114485-63-1
5-(Methoxyimino-methyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid 1-chloro-ethyl ester

: 139886-32-1
milameline

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / 0.5 h / Heating

2: Et₃N / dimethylformamide / 3 h / Ambient temperature

With triethylamine; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/0223-5234(91)90128-A

Reference yield:

: 139886-03-6
RU 35963

: 74-88-4
methyl iodide

: 139886-32-1
milameline

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; for 3h; Ambient temperature;
DOI:10.1016/0223-5234(91)90128-A

Reference yield:

: 139886-32-1
milameline

: 139886-03-6
RU 35963

Guidance literature:: Multi-step reaction with 2 steps

1: 1,2-dichloro-ethane / 2 h / Heating

2: methanol / 0.5 h / Heating

In methanol; 1,2-dichloro-ethane;
DOI:10.1016/0223-5234(91)90128-A