BENZYL 1,6-DIMETHYL-2-OXO-4-PHENYL-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE

Base Information

Chemical Name:BENZYL 1,6-DIMETHYL-2-OXO-4-PHENYL-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE
CAS No.:60750-24-5
Molecular Formula:C20H20N2O3
Molecular Weight:336.39
Hs Code.:

Synonyms:1,6-dimethyl-2-oxo-4-phenyl-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid benzyl ester;

Suppliers and Price of BENZYL 1,6-DIMETHYL-2-OXO-4-PHENYL-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of BENZYL 1,6-DIMETHYL-2-OXO-4-PHENYL-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE

Chemical Property:

Melting Point:119-120 °C
Boiling Point:542.9±50.0 °C(Predicted)
PKA:11.09±0.70(Predicted)
PSA：58.64000
Density:1.193±0.06 g/cm3(Predicted)
LogP:3.66680

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of BENZYL 1,6-DIMETHYL-2-OXO-4-PHENYL-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE

There total 2 articles about BENZYL 1,6-DIMETHYL-2-OXO-4-PHENYL-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 5396-89-4
benzyl acetoacetate

: 100-52-7
benzaldehyde

: 598-50-5
N-Methylurea

: 60750-24-5
benzyl 1,6-dimethyl-4-phenyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Guidance literature:: With ytterbium(III) triflate; In acetonitrile; at 120 ℃; for 0.333333h; microwave irradiation;
DOI:10.1016/j.tet.2005.12.061

Reference yield:

: 60750-24-5
benzyl 1,6-dimethyl-4-phenyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Guidance literature:: Acetessigsaeure-benzylester, Methylharnstoff, Benzaldehyd;
DOI:10.1007/BF00906765

Reference yield: 85.0%

: 60750-24-5
benzyl 1,6-dimethyl-4-phenyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

: 60750-38-1
1,2,3,4-tetrahydro-1,6-dimethyl-2-oxo-4-phenylpyrimidine-5-carboxylic acid

Guidance literature:: With hydrogen; acetic acid; palladium on activated charcoal; In ethanol; at 40 - 45 ℃; atmospheric pressure;
DOI:10.1016/j.tet.2005.12.061