Benzaldehyde, 2-ethyl-4-methoxy-

Base Information

• Chemical Name: Benzaldehyde, 2-ethyl-4-methoxy-
• CAS No.: 6161-69-9
• Molecular Formula: C10H12O2
• Molecular Weight: 164.204
• Mol file: 6161-69-9.mol

Synonyms:2-ethyl-4-methoxy-benzaldehyde;2-Ethyl-4-methoxy-benzaldehyd;2-Aethyl-4-methoxy-benzaldehyd;

Chemical Property of Benzaldehyde, 2-ethyl-4-methoxy-

Chemical Property:

• PSA: 26.30000
• LogP: 2.07010

Purity/Quality:

95% ^*data from raw suppliers

2-ethyl-4-methoxybenzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzaldehyde, 2-ethyl-4-methoxy-

There total 8 articles about Benzaldehyde, 2-ethyl-4-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

triethyl borane (97-94-9) + 2-bromo-4-methoxybenzaldehyde (43192-31-0) → 2-ethyl-4-methoxybenzaldehyde (6161-69-9)

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate; In tetrahydrofuran; at 68 ℃; for 3h; Inert atmosphere;

Reference yield:

3-ethylphenol (620-17-7) → 2-ethyl-4-methoxybenzaldehyde (6161-69-9)

Guidance literature:

Multi-step reaction with 2 steps

1: benzene; AlCl₃; HCl / und Behandeln der Reaktionsloesung mit kalter wss.Schwefelsaeure

2: KOH; aqueous methanol

With hydrogenchloride; methanol; potassium hydroxide; aluminium trichloride; benzene;

DOI:10.1021/ja01248a036

Reference yield:

3-ethylanisole (10568-38-4) → 2-ethyl-4-methoxybenzaldehyde (6161-69-9)

Guidance literature:

With hydrogenchloride; aluminium trichloride; benzene; und Erhitzen der Reaktionsloesung mit verd.wss.Salzsaeure;

DOI:10.1021/ja01248a036

upstream raw materials:

2-ethyl-4-hydroxybenzaldehyde

dimethyl sulfate

3-ethylanisole

dicyanozinc

Refernces

• 1、 Tietze, Lutz F.,Vock, Carsten A.,Krimmelbein, Ilga K.,Nacke, Linda. "Synthesis of novel structurally simplified estrogen analogues with electron-donating groups in ring A". experimental part. p. 2040 - 2060. Retrieved 2009/12/27.