Ethyl 4-(2-aminoethyl)-phenylacetate

Base Information

• Chemical Name: Ethyl 4-(2-aminoethyl)-phenylacetate
• CAS No.: 62910-65-0
• Molecular Formula: C12H17NO2
• Molecular Weight: 207.272
• DSSTox Substance ID: DTXSID801290915
• Mol file: 62910-65-0.mol

Synonyms:62910-65-0;ethyl 4-(2-aminoethyl)-phenylacetate;SCHEMBL10461745;QBISHRQLAUVUGO-UHFFFAOYSA-N;DTXSID801290915;Ethyl 4-(2-aminoethyl)benzeneacetate;ethyl 2-[4-(2-aminoethyl)phenyl]acetate;EN300-705883

Chemical Property of Ethyl 4-(2-aminoethyl)-phenylacetate

Chemical Property:

• XLogP3: 1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 207.125928785
• Heavy Atom Count: 15
• Complexity: 186

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCOC(=O)CC1=CC=C(C=C1)CCN

Technology Process of Ethyl 4-(2-aminoethyl)-phenylacetate

There total 1 articles about Ethyl 4-(2-aminoethyl)-phenylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 4-(2-aminoethyl)-phenylacetic acid ethyl ester (62910-65-0)

Guidance literature:

<4-Cyanomethyl-phenyl>-essigsaeure, 1) H2 bei 98at Anfangsdruck, 2) konz. HCl, 3) A. + HCl ;

Reference yield: 87.0%

benzene sulphochloride + 4-(2-aminoethyl)-phenylacetic acid ethyl ester (62910-65-0) → benzenesulphonic acid-[4-(2-hydroxyethyl)-phenethylamide] + ethyl 4-[2-(benzenesulphonylamino)-ethyl]-phenylacetate (108913-15-1)

Guidance literature:

Reference yield: 83.0%

4-(2-aminoethyl)-phenylacetic acid ethyl ester (62910-65-0) + 2-methoxy-5-chlorobenzoyl chloride (29568-33-0) → {4-[2-(5-Chloro-2-methoxy-benzoylamino)-ethyl]-phenyl}-acetic acid ethyl ester (62910-55-8)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 3h; Inert atmosphere;

DOI:10.1039/c3md00214d

Downstream raw materials:

{4-[2-(2-9H-Fluoren-9-yl-acetylamino)-ethyl]-phenyl}-acetic acid ethyl ester

4-[2-(2-methoxy-5-methylbenzamido)-ethyl]-phenylacetic acid

4-[2-(2-allyloxy-5-chlorobenzamido)-ethyl]-phenylacetic acid

4-[2-(5-chloro-2-phenoxybenzamido)-ethyl]-phenylacetic acid