1,2-BISMALEIMIDOETHANE

Base Information

• Chemical Name: 1,2-BISMALEIMIDOETHANE
• CAS No.: 5132-30-9
• Molecular Formula: C10H8 N2 O4
• Molecular Weight: 220.185
• Hs Code.: 2925190090
• Mol file: 5132-30-9.mol

Synonyms:Maleimide,N,N'-ethylenedi- (6CI,7CI,8CI); 1,2-Bismaleimidoethane; 1,2-Dimaleimidoethane;Ethylenebismaleimide; N,N'-Ethylenebismaleimide; N,N'-Ethylenedimaleimide; NSC41127

Chemical Property of 1,2-BISMALEIMIDOETHANE

Chemical Property:

• Appearance/Colour: Off White Solid
• Vapor Pressure: 1.54E-07mmHg at 25°C
• Melting Point: 193-194°C
• Boiling Point: 428.3°Cat760mmHg
• PKA: -2.11±0.20(Predicted)
• Flash Point: 215.7°C
• PSA: 74.76000
• Density: 1.51g/cm³
• LogP: -1.28780
• Storage Temp.: Refrigerator
• Solubility.: Chloroform

Purity/Quality:

98%,99%, ^*data from raw suppliers

Ethylene-bis-maleimide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,Xi
• Hazard Codes: Xn,Xi

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A short, sulfhydryl reactive homobifunctional crosslinking reagent.

Technology Process of 1,2-BISMALEIMIDOETHANE

There total 7 articles about 1,2-BISMALEIMIDOETHANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2,2'-(1,2-ethanediyl)bis(3a,4,7,7a-tetrahydro-4,7-epoxy-1,3-bishydroisoindole-1,3-dione) (32620-84-1) → 1,1'-(ethane-1,2-diyl)bis(1H-pyrrole-2,5-dione) (5132-30-9)

Guidance literature:

In 1,1,2,2-tetrachloroethane; at 120 ℃; for 12h;

DOI:10.1016/j.tetlet.2013.07.002

Reference yield: 64.0%

N-methoxycarbonylmaleimide (55750-48-6) + ethylenediamine (107-15-3,85404-18-8) → 1,1'-(ethane-1,2-diyl)bis(1H-pyrrole-2,5-dione) (5132-30-9)

Guidance literature:

With sodium hydrogencarbonate; In tetrahydrofuran; for 3h; Ambient temperature;

DOI:10.1021/jm00087a010

Reference yield:

N,N'-ethylene-bis-(3-carboxypropenamide) → 1,1'-(ethane-1,2-diyl)bis(1H-pyrrole-2,5-dione) (5132-30-9)

Guidance literature:

With sodium acetate; acetic anhydride; at 90 ℃; for 2.5h;

DOI:10.1002/anie.201301122

upstream raw materials:

N,N'-bis(3-carboxy-1-oxo-2-prop-2-enyl)ethylenediamine

N-methoxycarbonylmaleimide

ethylenediamine

2,2'-(1,2-ethanediyl)bis(3a,4,7,7a-tetrahydro-4,7-epoxy-1,3-bishydroisoindole-1,3-dione)

Downstream raw materials:

N-phenyl-maleimide

N,N'-bis(3-carboxy-1-oxo-2-prop-2-enyl)ethylenediamine

Refernces

• 1、 Tan, Xue-Jie,Cheng, Shuang-Shuang,Shi, Yan,Xing, Dian-Xiang,Liu, Yun,Li, Hui,Feng, Wen-Quan,Yang, Jian-Bo. "Hydrolytic degradation of N,N′-ethylenedimaleimide: Crystal structures of key intermediates and proposed mechanisms". . p. 514 - 521. Retrieved 2016.
• 2、 Mandal, Tanumoy,Das, Sanju,De Sarkar, Suman. "Nickel(II) Tetraphenylporphyrin as an Efficient Photocatalyst Featuring Visible Light Promoted Dual Redox Activities". supporting information. p. 3200 - 3209. Retrieved 2019/05/16.