1-Pyrrolidinecarboximidic acid, 4,4-dimethyl-1-(phenylmethyl)-2-pentynyl ester

Base Information

• Chemical Name: 1-Pyrrolidinecarboximidic acid, 4,4-dimethyl-1-(phenylmethyl)-2-pentynyl ester
• CAS No.: 62969-90-8
• Molecular Formula: C19H26N2O
• Molecular Weight: 298.428
• Mol file: 62969-90-8.mol

Synonyms:

Chemical Property of 1-Pyrrolidinecarboximidic acid, 4,4-dimethyl-1-(phenylmethyl)-2-pentynyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Pyrrolidinecarboximidic acid, 4,4-dimethyl-1-(phenylmethyl)-2-pentynyl ester

There total 1 articles about 1-Pyrrolidinecarboximidic acid, 4,4-dimethyl-1-(phenylmethyl)-2-pentynyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pyrrolidine-1-carbonitrile (1530-88-7) + 5,5-dimethyl-1-phenyl-3-hexyn-2-ol (62969-96-4) → Pyrrolidine-1-carboximidic acid 1-benzyl-4,4-dimethyl-pent-2-ynyl ester (62969-90-8)

Guidance literature:

With potassium hydride; In tetrahydrofuran; paraffin; for 20h; Yield given; Ambient temperature;

DOI:10.1021/ja00522a052

Reference yield: 21.0%

Pyrrolidine-1-carboximidic acid 1-benzyl-4,4-dimethyl-pent-2-ynyl ester (62969-90-8) → N-pyrrolidinecarboxamide (4736-71-4) + 6-tert-butyl-3-phenyl-2(1H)-pyridinone (62969-84-0) + N-<(3Z,5E)-2,2-dimethyl-6-phenyl-3,5-hexadien-3-yl>-1-pyrrolidinecarboxamide (62969-98-6)

Guidance literature:

With 5,5-dimethyl-1-phenyl-3-hexyn-2-ol; In decalin; at 90 - 110 ℃; for 11h; Product distribution; other solvent (xylene), other temperature (140 deg C), other time (5 h);

DOI:10.1021/ja00522a052

Reference yield:

Pyrrolidine-1-carboximidic acid 1-benzyl-4,4-dimethyl-pent-2-ynyl ester (62969-90-8) → 6-tert-butyl-3-phenyl-2(1H)-pyridinone (62969-84-0)

Guidance literature:

In xylene; for 12h; Yield given; Heating;

DOI:10.1021/ja00522a052

upstream raw materials:

pyrrolidine-1-carbonitrile

5,5-dimethyl-1-phenyl-3-hexyn-2-ol

Downstream raw materials:

N-pyrrolidinecarboxamide

6-tert-butyl-3-phenyl-2(1H)-pyridinone

N-<(3Z,5E)-2,2-dimethyl-6-phenyl-3,5-hexadien-3-yl>-1-pyrrolidinecarboxamide