3-Thiopheneacetic acid, a-hydroxy-, (R)-

Base Information

Chemical Name:3-Thiopheneacetic acid, a-hydroxy-, (R)-
CAS No.:63075-39-8
Molecular Formula:C6H6O3S
Molecular Weight:158.17500
Hs Code.:

Synonyms:(R)-hydroxy-[3]thienyl-acetic acid;(R)-Hydroxy-[3]thienyl-essigsaeure;(R)-Hydroxy-thiophen-3-yl-acetic acid;(-)-3-thienylglycolic acid;

Suppliers and Price of 3-Thiopheneacetic acid, a-hydroxy-, (R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-Thiopheneacetic acid, a-hydroxy-, (R)-

Chemical Property:

PSA：85.77000
LogP:0.86610

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-Thiopheneacetic acid, a-hydroxy-, (R)-

There total 4 articles about 3-Thiopheneacetic acid, a-hydroxy-, (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 82069-44-1
3-thienyl cyanohydrin

: 22098-20-0,63075-39-8,128572-14-5
(S)-2-hydroxy-2-(thiophen-3-yl)acetic acid

: 63075-39-8
(R)-(-)-3-thienylglycolic acid

Guidance literature:: With phosphate buffer; nitrilase I; In methanol; at 37 ℃; pH=8; Title compound not separated from byproducts.;
DOI:10.1021/ja0259842

Reference yield:

: 82069-44-1
3-thienyl cyanohydrin

: 22098-20-0,63075-39-8,128572-14-5
(S)-2-hydroxy-2-(thiophen-3-yl)acetic acid

: 63075-39-8
(R)-(-)-3-thienylglycolic acid

Guidance literature:: With phosphate buffer; nitrilase I; In methanol; at 37 ℃; pH=8; Title compound not separated from byproducts.;
DOI:10.1021/ja0259842

Reference yield:

: 498-62-4
3-thiophene carboxaldehyde

: 22098-20-0,63075-39-8,128572-14-5
(S)-2-hydroxy-2-(thiophen-3-yl)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: CH₃COOH / methanol / 1 h / 0 °C

2: nitrilase I; phosphate buffer / methanol / 37 °C / pH 8

With phosphate buffer; nitrilase I; acetic acid; In methanol;
DOI:10.1021/ja0259842