(4S)-4-Propyloxolan-2-one

Base Information

Chemical Name:(4S)-4-Propyloxolan-2-one
CAS No.:63095-60-3
Molecular Formula:C7H12O2
Molecular Weight:128.171
Hs Code.:
DSSTox Substance ID:DTXSID00548558
Wikidata:Q82427302

Synonyms:63095-60-3;(4S)-4-Propyloxolan-2-one;(S)-4-Propyldihydrofuran-2(3H)-one;2(3H)-Furanone, dihydro-4-propyl-, (S)-;DTXSID00548558;(4S)-Dihydro-4-propyl-2(3H)-furanone;G68355

Suppliers and Price of (4S)-4-Propyloxolan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 10 raw suppliers

Chemical Property of (4S)-4-Propyloxolan-2-one

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:128.083729621
Heavy Atom Count:9
Complexity:110

Purity/Quality:: NLT 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCC1CC(=O)OC1
Isomeric SMILES:CCC[C@H]1CC(=O)OC1

Technology Process of (4S)-4-Propyloxolan-2-one

There total 2 articles about (4S)-4-Propyloxolan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 21963-27-9
4-propyl-5H-furan-2-one

: 63095-51-2
(+)-(R)-4-propyl-4,5-dihydrofuran-2(3H)-one

: 63095-60-3
(-)-(S)-β-propyl-γ-butyrolactone

Guidance literature:: With water; (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine); copper(l) chloride; sodium t-butanolate; In toluene; tert-butyl alcohol; at 0 - 30 ℃; Overall yield = 78.65 percent; Overall yield = 400 g; Inert atmosphere;

Reference yield:

: (2R,3S)-3,4-Dimethyl-2-phenyl-6-propyl-3,4,6,7-tetrahydro-2H-furo[3,2-f][1,4]oxazepin-5-one

: 63095-51-2
(+)-(R)-4-propyl-4,5-dihydrofuran-2(3H)-one

: 63095-60-3
(-)-(S)-β-propyl-γ-butyrolactone

Guidance literature:: In sulfuric acid; water; acetic acid; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Heating;
DOI:10.1246/cl.1980.635

Reference yield:

: 63095-60-3
(-)-(S)-β-propyl-γ-butyrolactone

: 357336-99-3,943986-70-7
((2S)-2-[(4S)-2-oxo-4-propyltetrahydro-1H-pyrrol-1-yl]butanamide)

Guidance literature:: Multi-step reaction with 2 steps

1: trimethylsilyl bromide / dichloromethane / 6 h / 20 °C / Inert atmosphere

2: sodium carbonate / ethanol / 16 h / 50 °C

With trimethylsilyl bromide; sodium carbonate; In ethanol; dichloromethane;
DOI:10.1016/j.tet.2020.131273