Brivaracetam (alfaR, 4S)-Isomer

Base Information

Chemical Name:Brivaracetam (alfaR, 4S)-Isomer
CAS No.:357336-99-3
Molecular Formula:C11H20N2O2
Molecular Weight:212.29
Hs Code.:

Synonyms:Brivaracetam (alfaR, 4S)-Isomer;2R-2-[(4S)-2-oxo-4-propylpyrrolidin-1-yl]butanamide

Suppliers and Price of Brivaracetam (alfaR, 4S)-Isomer

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
αR,4S-Brivaracetam
25mg
$ 2665.00

TRC
αR,4S-Brivaracetam
10mg
$ 1185.00

Total 18 raw suppliers

Chemical Property of Brivaracetam (alfaR, 4S)-Isomer

Chemical Property:

Boiling Point:409.3±28.0 °C(Predicted)
PKA:15.74±0.50(Predicted)
PSA：63.40000
Density:1.062±0.06 g/cm3(Predicted)
LogP:1.53710
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

NLT 98% ^*data from raw suppliers

αR,4S-Brivaracetam ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses αR,4S-Brivaracetam acts as a reagent for the preparation of 2-Oxo-1-pyrrolidine derivatives and their anticonvulsants activity. Also an impurity of Brivaracetam (B677645), a 4-n-propyl analog of levetiracetam (L331500), and a racetam derivative with anticonvulsant properties.

Technology Process of Brivaracetam (alfaR, 4S)-Isomer

There total 202 articles about Brivaracetam (alfaR, 4S)-Isomer which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.3%

: 357338-13-7
(2S)-4,5-dehydro-(2-oxo-4-n-propyl-1-pyrrolidinyl)-2-butanamide

: 357336-20-0,357336-99-3,943986-70-7
brivaracetam

Guidance literature:: With (R)-((4,4’-bi-1,3-benzodioxole)-5,5’-diyl)bis(bis(3,5-di-t-butyl-4-methoxyphenyl))phosphine; copper(l) chloride; sodium t-butanolate; In toluene; at -40 ℃; for 24h; Inert atmosphere;

Reference yield: 93.0%

: (R)-N-((S)-1-amino-1-oxobutan-2-yl)-3-(chloromethyl)hexanamide

: 357336-20-0,357336-99-3,943986-70-7
brivaracetam

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran;

Reference yield: 92.0%

: 7324-11-0,53726-14-0,104652-77-9,143164-46-9
(S)-2-amino-butanamide

: C₇H₁₃IO₂

: 357336-20-0,357336-99-3,943986-70-7
brivaracetam

Guidance literature:: C₇H₁₃IO₂; With 1,1'-carbonyldiimidazole; In toluene; at 10 - 20 ℃; for 0.166667h; Inert atmosphere;

(S)-2-amino-butanamide; In toluene; at 10 - 20 ℃;