4H-(1,2,4)Triazolo(4,3-a)(1,5)benzodiazepin-5-amine, N,1-diphenyl-N-ethyl-

Base Information

Chemical Name:4H-(1,2,4)Triazolo(4,3-a)(1,5)benzodiazepin-5-amine, N,1-diphenyl-N-ethyl-
CAS No.:133118-19-1
Molecular Formula:C₂₄H₂₁N₅
Molecular Weight:379.464
Hs Code.:
DSSTox Substance ID:DTXSID40157961
Nikkaji Number:J358.153E

Synonyms:BRN 4210896;4H-(1,2,4)Triazolo(4,3-a)(1,5)benzodiazepin-5-amine, N,1-diphenyl-N-ethyl-;133118-19-1;N,1-Diphenyl-N-ethyl-4H-(1,2,4)triazolo(4,3-a)(1,5)benzodiazepin-5-amine;DTXSID40157961;LS-156296;1-Phenyl-5-(ethylphenylamino)-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepine

Suppliers and Price of 4H-(1,2,4)Triazolo(4,3-a)(1,5)benzodiazepin-5-amine, N,1-diphenyl-N-ethyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 4H-(1,2,4)Triazolo(4,3-a)(1,5)benzodiazepin-5-amine, N,1-diphenyl-N-ethyl-

Chemical Property:

Vapor Pressure:1.12E-14mmHg at 25°C
Boiling Point:606.9°Cat760mmHg
Flash Point:320.9°C
Density:1.22g/cm³
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:379.17969569
Heavy Atom Count:29
Complexity:566

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(C1=NC2=CC=CC=C2N3C(=NN=C3C4=CC=CC=C4)C1)C5=CC=CC=C5

Technology Process of 4H-(1,2,4)Triazolo(4,3-a)(1,5)benzodiazepin-5-amine, N,1-diphenyl-N-ethyl-

There total 3 articles about 4H-(1,2,4)Triazolo(4,3-a)(1,5)benzodiazepin-5-amine, N,1-diphenyl-N-ethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 12.0%

: 133118-32-8
N-ethyl-N-phenyl-4-(methylthio)-3H-1,5-benzodiazepin-2-amine

: 613-94-5
benzoic acid hydrazide

: 133118-19-1
N-ethyl-N-phenyl-1-phenyl-4H-<1,2,4>triazolo<4,3-a><1,5>benzodiazepin-5-amine

: 133118-28-2
6,12-diphenyl-9H-bis<1,2,4>triazolo<4,3-a:3',4'-d><1,5>benzodiazepine

Guidance literature:: In various solvent(s); at 200 ℃; for 2h;
DOI:10.1016/0223-5234(90)90133-N

Reference yield:

: 4-<(N-ethyl-N-phenyl)amino>-1,3-dihydro-2H-1,5-benzodiazepin-2-thione

: 133118-19-1
N-ethyl-N-phenyl-1-phenyl-4H-<1,2,4>triazolo<4,3-a><1,5>benzodiazepin-5-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) THF, toluene, 50 deg C, 45 min, 2.) 50 deg C, 90 min

2: 69 percent / various solvent(s) / 2 h / 200 °C

With sodium hydride; In various solvent(s);
DOI:10.1016/0223-5234(90)90133-N

Reference yield:

: 62537-65-9
4-(N-ethyl-anilino)-1,3-dihydro-benzo[b][1,4]diazepin-2-one

: 133118-19-1
N-ethyl-N-phenyl-1-phenyl-4H-<1,2,4>triazolo<4,3-a><1,5>benzodiazepin-5-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 93 percent / Lawesson's reagent / toluene / 0.5 h / 100 °C

2: 1.) NaH / 1.) THF, toluene, 50 deg C, 45 min, 2.) 50 deg C, 90 min

3: 69 percent / various solvent(s) / 2 h / 200 °C

With Lawessons reagent; sodium hydride; In toluene;
DOI:10.1016/0223-5234(90)90133-N