Faicar

Base Information

Chemical Name:Faicar
CAS No.:13018-54-7
Molecular Formula:C10H15 N4 O9 P
Molecular Weight:366.22
Hs Code.:
UNII:KNY2D67FT5
DSSTox Substance ID:DTXSID50156384
Nikkaji Number:J602.393B
Wikipedia:5-Formamidoimidazole-4-carboxamide_ribotide
Wikidata:Q2817110
Pharos Ligand ID:XG7QPCFZHG6T
Metabolomics Workbench ID:37801
ChEMBL ID:CHEMBL521310
Mol file:13018-54-7.mol

Synonyms:5-formamidoimidazole-4-carboxamide ribotide;FAICAR

Suppliers and Price of Faicar

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
FAICAR~85%
5mg
$ 740.00

TRC
FAICAR~85%
1mg
$ 190.00

AK Scientific
Faicar
2mg
$ 765.00

Total 8 raw suppliers

Chemical Property of Faicar

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:941.6°Cat760mmHg
Flash Point:523.2°C
PSA：219.76000
Density:2.17g/cm³
LogP:-1.37140
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:DMSO (Slightly), Water (Slightly)
XLogP3:-4
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:6
Exact Mass:366.05766507
Heavy Atom Count:24
Complexity:531

Purity/Quality:

97% ^*data from raw suppliers

FAICAR~85% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=NC(=C(N1C2C(C(C(O2)COP(=O)(O)O)O)O)NC=O)C(=O)N
Isomeric SMILES:C1=NC(=C(N1[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O)NC=O)C(=O)N
Uses FAICAR is the derivative of AICAR (A611700), which is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.

Technology Process of Faicar

There total 3 articles about Faicar which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 64-18-6
formic acid

: 3031-94-5
5-aminoimidazole-4-carboxamide ribonucleotide

: 13018-54-7
5-aminoformylimidazole-4-carboxamide 1-β-D-ribofuranosyl 5'-monophosphate

Guidance literature:: With sodium formate; acetic anhydride; at 20 - 50 ℃; for 0.5h;
DOI:10.1021/jacs.9b00241

Reference yield:

: 3031-94-5
5-aminoimidazole-4-carboxamide ribonucleotide

: N¹⁰-formyl-dihydrofolic acid

: 13018-54-7
5-aminoformylimidazole-4-carboxamide 1-β-D-ribofuranosyl 5'-monophosphate

: 4033-27-6
(S)-2-{4-[(2-Amino-4-oxo-3,4,7,8-tetrahydro-pteridin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid

Guidance literature:: With Dimethylarsinic acid; AICAR transformylase wild type; ethanolamine; Tris buffer; at 25 ℃; pH=7.5; Further Variations:; Reagents; pH-values; Enzyme kinetics;
DOI:10.1021/ja010014k