Chlorodifluoroacetyl fluoride

Base Information

• Chemical Name: Chlorodifluoroacetyl fluoride
• CAS No.: 354-27-8
• Molecular Formula: C2Cl F3 O
• Molecular Weight: 132.47
• Hs Code.: 2915900090
• European Community (EC) Number: 206-554-1
• DSSTox Substance ID: DTXSID6059865
• Nikkaji Number: J193.828B
• Wikidata: Q81988976
• Mol file: 354-27-8.mol

Synonyms:Chlorodifluoroacetyl fluoride;354-27-8;2-chloro-2,2-difluoroacetyl fluoride;Acetyl fluoride, chlorodifluoro-;EINECS 206-554-1;Acetyl fluoride, 2-chloro-2,2-difluoro-;SCHEMBL1145086;DTXSID6059865;MFCD00153743;AKOS016015372

Chemical Property of Chlorodifluoroacetyl fluoride

Chemical Property:

• Vapor Pressure: 165mmHg at 25°C
• Boiling Point: 64.3°Cat760mmHg
• Flash Point: °C
• PSA: 17.07000
• Density: 1.532g/cm³
• LogP: 1.31410
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 131.9589768
• Heavy Atom Count: 7
• Complexity: 90.9

Purity/Quality:

98%min ^*data from raw suppliers

CHLORODIFLUOROACETYL FLUORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: 20-35-37
• Safety Statements: 23-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(=O)(C(F)(F)Cl)F

Technology Process of Chlorodifluoroacetyl fluoride

There total 45 articles about Chlorodifluoroacetyl fluoride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

1,3-dichloro-1,1,3,3-tetrafluoro-propan-2-one (127-21-9) → Dichlorodifluoromethane (75-71-8) + chlorodifluoroacetyl fluoride (354-27-8) + C3Cl3F5O (152239-91-3)

Guidance literature:

With chlorine monofluoride; cesium fluoride; 1.) -140 degC to -65 degC over 6 h, 2.) -65 degC, 4 h;

DOI:10.1016/S0022-1139(00)80070-6

Reference yield: 70.0%

Chlorotrifluoroethylene (79-38-9,9036-80-0) + C3Cl2F6O (22675-69-0) → chlorotrifluoromethane (75-72-9) + trifluoroacetyl fluoride (354-34-7) + chlorodifluoroacetyl fluoride (354-27-8) + 1-Chloro-2-(2,2-dichloro-1,1,2-trifluoro-ethoxy)-1,1,2,3,3,3-hexafluoro-propane

Guidance literature:

In trichlorofluoromethane; for 20h; Further byproducts given; -140 degC to 22 degC;

DOI:10.1016/S0022-1139(00)80070-6

Reference yield: 67.0%

2-chloro-1,1,2,2-tetrafluoro-2-methoxyethane (404582-64-5) → methylene chloride (74-87-3) + chlorodifluoroacetyl fluoride (354-27-8) + metyhyl chlorodifluoroacetate (1514-87-0)

Guidance literature:

With aluminum(III) fluoride; antimony pentafluoride; at 200 ℃; for 2h;

DOI:10.1016/S0022-1139(02)00321-4

upstream raw materials:

Chlorotrifluoroethylene

chlordifluoroacetyl chloride

polytetrafluoroethylene

1,1'-dichloro-2,2'-difluoroethene

Downstream raw materials:

2-chloro-2,2-difluoroacetic acid

metyhyl chlorodifluoroacetate

Dichlorodifluoromethane

1,2-dichloro-1,1,2,2-tetrafluoroethane

Refernces

• 1、 -. "Continuous production of chlorodifluoroacetyl fluoride via chlorotrifluoroethylene oxidation". Page/Page column 2-3. . Retrieved 2008/06/13.
• 2、 Quan, Heng-Dao,Tamura, Masanori,Gao, Ren-Xiao,Sekiya, Akira. "Defluorination of homologous chlorofluoroethers to chlorofluoroacetates". . p. 131 - 134. Retrieved 2007/10/03.