2,4-Difluorocinnamic acid

Base Information

Chemical Name:2,4-Difluorocinnamic acid
CAS No.:94977-52-3
Molecular Formula:C9H6F2O2
Molecular Weight:184.142
Hs Code.:29163990
European Community (EC) Number:627-327-7,670-869-4
Nikkaji Number:J911.585D,J1.424.449B
Wikidata:Q76305731
Mol file:94977-52-3.mol

Synonyms:2,4-Difluorocinnamic acid;94977-52-3;trans-2,4-Difluorocinnamic acid;774-73-2;(E)-3-(2,4-difluorophenyl)acrylic acid;(E)-3-(2,4-difluorophenyl)prop-2-enoic acid;(2E)-3-(2,4-difluorophenyl)prop-2-enoic acid;3-(2,4-difluorophenyl)prop-2-enoic acid;3-(2,4-Difluorophenyl)acrylic Acid;2,4-Difluorocinnamicacid;2-Propenoic acid, 3-(2,4-difluorophenyl)-, (2E)-;2,4-difluoro-cinnamic acid;(2e)-3-(2,4-difluorophenyl)acrylic acid;2,4-Difluorzimtsaure;SCHEMBL716629;(E)-2,4-difluorocinnamic acid;PQDXPFJQTKGTFP-DUXPYHPUSA-;AMY6605;3-(2,4-Difluorophenyl)acrylicAcid;BBL021022;CK1148;MFCD00010317;STK893728;AKOS000138469;AKOS025149358;PS-6472;trans-2,4-Difluorocinnamic acid, 97%;trans-2,4-Difluorocinnamic acid, 98%;NCGC00337014-01;AC-26149;AS-58566;BP-12672;(E)-3-(2,4-Difluoro-phenyl)-acrylic acid;CS-0037496;4,4-DIFLUOROHEPTANEDIOICACIDDIETHYLESTER;D72623;EN300-320894;AB01330301-02;(2E)-3-(2,4-Difluorophenyl)-2-propenoic acid #;J-507215;InChI=1/C9H6F2O2/c10-7-3-1-6(8(11)5-7)2-4-9(12)13/h1-5H,(H,12,13)/b4-2+

Suppliers and Price of 2,4-Difluorocinnamic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,4-Difluorocinnamic Acid
1g
$ 75.00

TCI Chemical
2,4-Difluorocinnamic Acid >98.0%(GC)(T)
5g
$ 78.00

SynQuest Laboratories
trans-2,4-Difluorocinnamic acid 98%
25 g
$ 56.00

SynQuest Laboratories
trans-2,4-Difluorocinnamic acid 98%
5 g
$ 16.00

SynQuest Laboratories
trans-2,4-Difluorocinnamic acid 98%
50 g
$ 108.00

Sigma-Aldrich
trans-2,4-Difluorocinnamic acid 98%
5g
$ 109.00

Oakwood
trans-2,4-Difluorocinnamic acid 98%
5g
$ 15.00

Oakwood
trans-2,4-Difluorocinnamic acid 98%
100g
$ 185.00

Frontier Specialty Chemicals
trans-2,4-Difluorocinnamic acid 98%
5g
$ 118.00

Frontier Specialty Chemicals
trans-2,4-Difluorocinnamic acid 98%
1g
$ 30.00

Total 45 raw suppliers

Chemical Property of 2,4-Difluorocinnamic acid

Chemical Property:

Appearance/Colour:White to pale yellow powder
Vapor Pressure:0.015mmHg at 25°C
Melting Point:216-218 °C
Refractive Index:1.46
Boiling Point:272 °C at 760 mmHg
PKA:4.29±0.13(Predicted)
Flash Point:118.3 °C
PSA：37.30000
Density:1.379 g/cm³
LogP:2.06260
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:184.03358575
Heavy Atom Count:13
Complexity:216

Purity/Quality:

99% ^*data from raw suppliers

2,4-Difluorocinnamic Acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-37/39-26/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC(=C(C=C1F)F)C=CC(=O)O
Isomeric SMILES:C1=CC(=C(C=C1F)F)/C=C/C(=O)O
Uses trans-2,4-Difluorocinnamic acid may be used in chemical synthesis.

Technology Process of 2,4-Difluorocinnamic acid

There total 7 articles about 2,4-Difluorocinnamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 4519-40-8
2,3-difluoroanilline

: 5329-14-6
aminosulfonic acid

: 79-10-7
acrylic acid

: 94977-52-3
2,4-Difluorocinnamic acid

Guidance literature:: With sulfuric acid; sodium nitrite; palladium diacetate; In water;

Reference yield: 64.0%

: 94977-52-3
2,4-Difluorocinnamic acid

Guidance literature:: With piperidine; In pyridine; at 50 - 70 ℃; for 18h;

Reference yield: 54.0%

: 348-57-2
2,4-difluorobromobenzene

: 79-10-7
acrylic acid

: 94977-52-3
2,4-Difluorocinnamic acid

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; potassium carbonate; In N,N-dimethyl-formamide; at 145 - 150 ℃; for 6h;