N,N,1-trimethylindole-2-carboxamide

Base Information

Chemical Name:N,N,1-trimethylindole-2-carboxamide
CAS No.:41979-55-9
Molecular Formula:C12H14N2O
Molecular Weight:202.256
Hs Code.:
NSC Number:165232
DSSTox Substance ID:DTXSID80304275
Wikidata:Q82050098
Mol file:41979-55-9.mol

Synonyms:N,N,1-trimethylindole-2-carboxamide;41979-55-9;NSC165232;SCHEMBL8568554;DTXSID80304275;AKOS016908067;NSC-165232;Z737228682

Suppliers and Price of N,N,1-trimethylindole-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of N,N,1-trimethylindole-2-carboxamide

Chemical Property:

Vapor Pressure:4.99E-06mmHg at 25°C
Refractive Index:1.572
Boiling Point:381.7 °C at 760 mmHg
Flash Point:184.6 °C
Density:1.09 g/cm³
XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:202.110613074
Heavy Atom Count:15
Complexity:252

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1C2=CC=CC=C2C=C1C(=O)N(C)C

Technology Process of N,N,1-trimethylindole-2-carboxamide

There total 7 articles about N,N,1-trimethylindole-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 27421-51-8
1-methyl-1H-indole-2-carboxaldehyde

: 124-40-3
dimethyl amine

: 41979-55-9
N,N-dimethyl-1-methylindole-2-carboxamide

Guidance literature:: With 1,3-Diiodo-5,5-dimethyl-2,4-imidazolidinedione; potassium carbonate; In tetrachloromethane; water; at 20 ℃; Inert atmosphere;
DOI:10.1055/s-0031-1290659

Reference yield: 56.0%

: 603-76-9
1-methylindole

: 79-44-7
N,N-Dimethylcarbamoyl chloride

: 41979-55-9
N,N-dimethyl-1-methylindole-2-carboxamide

Guidance literature:: 1-methylindole; With tert.-butyl lithium; In tetrahydrofuran; at -78 - 20 ℃; for 0.5h;

N,N-Dimethylcarbamoyl chloride; In tetrahydrofuran; at -78 - 20 ℃; for 1h;
DOI:10.1039/d1ob02294f