2-Fluoro-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol

Base Information

Chemical Name:2-Fluoro-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
CAS No.:16205-32-6
Molecular Formula:C18H23 F O2
Molecular Weight:290.37
Hs Code.:
NSC Number:97849
DSSTox Substance ID:DTXSID10936629
Mol file:16205-32-6.mol

Synonyms:2-fluoroestradiol

Suppliers and Price of 2-Fluoro-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2-Fluoro-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol

Chemical Property:

Vapor Pressure:7.23E-08mmHg at 25°C
Melting Point:177 °C
Boiling Point:421.8°Cat760mmHg
PKA:9.03±0.60(Predicted)
Flash Point:208.9°C
PSA：40.46000
Density:1.225g/cm³
LogP:3.74830
XLogP3:4.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:290.16820813
Heavy Atom Count:21
Complexity:414

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC3C(C1CCC2O)CCC4=CC(=C(C=C34)F)O

Technology Process of 2-Fluoro-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol

There total 19 articles about 2-Fluoro-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1093411-48-3
estradiol

: 16205-32-6
2-fluoro-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol

: 1881-37-4
4-fluoro-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol

Guidance literature:: With Selectfluor; In methanol; at 20 ℃; for 0.5h;
DOI:10.1016/j.jfluchem.2007.11.006

Reference yield: 63.0%

: 50-28-2
estradiol

: 10α-fluoro-8a-estra-1,4-diene-17β-ol-3-one

: 1427-61-8
10β-Fluoro-3-oxo-1,4-estradien-17β-ol

: 1881-37-4
4-Fluoroestradiol

: 16205-32-6
2-Fluoroestradiol

Guidance literature:: With Selectfluor; In methanol; at 20 ℃; for 1h; regioselective reaction; Ionic liquid;
DOI:10.1016/j.jfluchem.2014.09.030