2-(1H-Benzimidazol-2-ylsulfanyl)-1-(4-fluorophenyl)ethanone

Base Information

Chemical Name:2-(1H-Benzimidazol-2-ylsulfanyl)-1-(4-fluorophenyl)ethanone
CAS No.:63529-32-8
Molecular Formula:C15H11FN2OS
Molecular Weight:286.33
Hs Code.:
DSSTox Substance ID:DTXSID701203212
ChEMBL ID:CHEMBL3634517

Synonyms:63529-32-8;ethanone, 2-(1h-benzimidazol-2-ylthio)-1-(4-fluorophenyl)-;CHEMBL3634517;2-(1H-Benzimidazol-2-ylsulfanyl)-1-(4-fluorophenyl)ethanone;DTXSID701203212;STL182828;AKOS002322140;Ethanone, 2-(2-benzimidazolylthio)-1-(4-fluorophenyl)-;F3328-0008;2-(1H-Benzimidazol-2-ylthio)-1-(4-fluorophenyl)ethanone;2-((1H-benzo[d]imidazol-2-yl)thio)-1-(4-fluorophenyl)ethanone;2-(1H-Benzimidazol-2-ylsulfanyl)-1-(4-fluorophenyl)ethanone #

Suppliers and Price of 2-(1H-Benzimidazol-2-ylsulfanyl)-1-(4-fluorophenyl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 2-(1H-Benzimidazol-2-ylsulfanyl)-1-(4-fluorophenyl)ethanone

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:286.05761231
Heavy Atom Count:20
Complexity:347

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)NC(=N2)SCC(=O)C3=CC=C(C=C3)F

Technology Process of 2-(1H-Benzimidazol-2-ylsulfanyl)-1-(4-fluorophenyl)ethanone

There total 7 articles about 2-(1H-Benzimidazol-2-ylsulfanyl)-1-(4-fluorophenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 134469-07-1
Benzimidazol-2-thiol

: 403-29-2
2-bromo-4'-fluoroacetophenone

: 63529-32-8
2-((1H-benzo[d]imidazol-2-yl)thio)-1-(4-fluorophenyl)ethan-1-one

Guidance literature:: With zinc(II) oxide; In neat (no solvent); at 25 - 30 ℃;
DOI:10.1002/ejoc.201601425

Reference yield:

: 2-((2-(4-fluorophenyl)-2-oxoethyl)thio)-1H-benzo[d]imidazol-3-ium sulfate salt

: 63529-32-8
2-((1H-benzo[d]imidazol-2-yl)thio)-1-(4-fluorophenyl)ethan-1-one

Guidance literature:: In water; at 20 ℃; for 2h;
DOI:10.1016/j.ejmech.2015.09.023

Reference yield:

: 403-42-9
1-(4-fluorophenyl)ethanone

: 134469-07-1
Benzimidazol-2-thiol

: 63529-32-8
2-((1H-benzo[d]imidazol-2-yl)thio)-1-(4-fluorophenyl)ethan-1-one

Guidance literature:: 1-(4-fluorophenyl)ethanone; Benzimidazol-2-thiol; With sulfuric acid; acetic acid; for 0.5h; Reflux;

With sodium carbonate; In water; at 20 ℃; for 2h;
DOI:10.3390/ijms17081221