5-Bromo-2-chloro-1-methoxy-3-nitrobenzene

Base Information

Chemical Name:5-Bromo-2-chloro-1-methoxy-3-nitrobenzene
CAS No.:63603-16-7
Molecular Formula:C7H5BrClNO3
Molecular Weight:266.47700
Hs Code.:
DSSTox Substance ID:DTXSID90501152
Wikidata:Q82353326

Synonyms:5-Bromo-2-chloro-1-methoxy-3-nitrobenzene;63603-16-7;DTXSID90501152;4-Bromo-1-chloro-2-methoxy-6-nitrobenzene

Suppliers and Price of 5-Bromo-2-chloro-1-methoxy-3-nitrobenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 5-Bromo-2-chloro-1-methoxy-3-nitrobenzene

Chemical Property:

Boiling Point:321.5±37.0 °C(Predicted)
PSA：55.05000
Density:1.737±0.06 g/cm3(Predicted)
LogP:3.54250
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:264.91413
Heavy Atom Count:13
Complexity:199

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC(=CC(=C1Cl)[N+](=O)[O-])Br

Technology Process of 5-Bromo-2-chloro-1-methoxy-3-nitrobenzene

There total 5 articles about 5-Bromo-2-chloro-1-methoxy-3-nitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 71001-78-0
3-nitro-4-chloro-5-methoxybenzoic acid

: 63603-16-7
2-chloro-3-nitro-5-bromoanisole

Guidance literature:: With bromine; mercury(II) oxide; In tetrachloromethane; for 5h; Irradiation;
DOI:10.1021/ja00353a027

Reference yield:

: 3943-74-6
4-hydroxy-3-methoxybenzoic acid methyl ester

: 63603-16-7
2-chloro-3-nitro-5-bromoanisole

Guidance literature:: Multi-step reaction with 4 steps

1: 74 percent / HNO₃, glacial acetic acid / acetic acid / 2 h / Ambient temperature

2: 88 percent / oxalyl chloride / dimethylformamide / -20 deg C; 80 deg C, 3 h

3: 30 g / KOH / ethanol; H₂O / 2 h / 80 °C

4: 60 percent / mercuric oxide, bromine / CCl₄ / 5 h / Irradiation

With potassium hydroxide; oxalyl dichloride; bromine; nitric acid; acetic acid; mercury(II) oxide; In tetrachloromethane; ethanol; water; acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/ja00353a027

Reference yield:

: 63603-09-8
methyl 4-chloro-3-methoxy-5-nitrobenzoate

: 63603-16-7
2-chloro-3-nitro-5-bromoanisole

Guidance literature:: Multi-step reaction with 2 steps

1: 30 g / KOH / ethanol; H₂O / 2 h / 80 °C

2: 60 percent / mercuric oxide, bromine / CCl₄ / 5 h / Irradiation

With potassium hydroxide; bromine; mercury(II) oxide; In tetrachloromethane; ethanol; water;
DOI:10.1021/ja00353a027