5-Hydroxydiclofenac

Base Information

Chemical Name:5-Hydroxydiclofenac
CAS No.:69002-84-2
Molecular Formula:C14H11Cl2NO3
Molecular Weight:312.152
Hs Code.:
UNII:GS38436703
DSSTox Substance ID:DTXSID00219059
Nikkaji Number:J341.706I
Wikidata:Q27126805
Metabolomics Workbench ID:60713
ChEMBL ID:CHEMBL1031
Mol file:69002-84-2.mol

Synonyms:(2-((2,6-dichlorophenyl)amino)-5-hydroxyphenyl)acetic acid;5-hydroxydiclofenac

Suppliers and Price of 5-Hydroxydiclofenac

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-HydroxyDiclofenac
5mg
$ 180.00

TRC
5-HydroxyDiclofenac
25mg
$ 360.00

Medical Isotopes, Inc.
5-HydroxyDiclofenac
1 mg
$ 490.00

Crysdot
2-(2-((2,6-Dichlorophenyl)amino)-5-hydroxyphenyl)aceticacid 97%
250mg
$ 1240.00

Crysdot
2-(2-((2,6-Dichlorophenyl)amino)-5-hydroxyphenyl)aceticacid 97%
100mg
$ 772.00

Crysdot
2-(2-((2,6-Dichlorophenyl)amino)-5-hydroxyphenyl)aceticacid 97%
50mg
$ 475.00

Cayman Chemical
5-hydroxy Diclofenac ≥98%
5mg
$ 411.00

Cayman Chemical
5-hydroxy Diclofenac ≥98%
1mg
$ 103.00

American Custom Chemicals Corporation
5-HYDROXY DICLOFENAC 95.00%
1MG
$ 427.35

American Custom Chemicals Corporation
5-HYDROXY DICLOFENAC 95.00%
10MG
$ 1593.90

Total 18 raw suppliers

Chemical Property of 5-Hydroxydiclofenac

Chemical Property:

Vapor Pressure:1.08E-08mmHg at 25°C
Melting Point:175-178?C
Refractive Index:1.689
Boiling Point:444.8 °C at 760 mmHg
Flash Point:222.8 °C
PSA：69.56000
Density:1.52 g/cm³
LogP:4.14270
Storage Temp.:Refrigerator
XLogP3:3.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:311.0115986
Heavy Atom Count:20
Complexity:332

Purity/Quality:

98%Min ^*data from raw suppliers

5-HydroxyDiclofenac ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C(=C1)Cl)NC2=C(C=C(C=C2)O)CC(=O)O)Cl

Technology Process of 5-Hydroxydiclofenac

There total 25 articles about 5-Hydroxydiclofenac which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 698357-97-0
2-[(2',6'-dichlorophenyl)amino]-5-hydroxyphenyl-N,N-dimethylacetamide

: 69002-84-2
2-(2-((2,6-dichlorophenyl)amino)-5-hydroxyphenyl)acetic acid

Guidance literature:: With sodium hydroxide; In ethanol; at 80 ℃; for 36h;
DOI:10.1021/jm030891w

Reference yield: 46.0%

: 15307-86-5
[2-(2,6-dichloroanilino)phenyl]acetic acid

: 69002-84-2
2-(2-((2,6-dichlorophenyl)amino)-5-hydroxyphenyl)acetic acid

Guidance literature:: With sodium hydrogensulfite; In water; acetonitrile; Electrolysis;
DOI:10.1021/ml400316p

Reference yield: 34.0%

: 15307-79-6
diclofenac sodium

: 64118-84-9
4'-hydroxydiclofenac

: 69002-84-2
2-(2-((2,6-dichlorophenyl)amino)-5-hydroxyphenyl)acetic acid

Guidance literature:: With glucose dehydrogenase; D-glucose; cytochrome P₄₅₀_BM₃R₄₇L/Y₅₁F/F₈₁W/F₈₇V/E₂₆₇V/I₄₀₁P mutant; β-nicotinamide adenine dinucleotide phosphate sodium salt; In aq. phosphate buffer; ethanol; at 25 ℃; for 2h; pH=7.5; Enzymatic reaction;
DOI:10.1002/chem.201502020