Technology Process of Benzeneacetic acid, 2-methoxy-, 1,1-dimethylethyl ester
There total 7 articles about Benzeneacetic acid, 2-methoxy-, 1,1-dimethylethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
bromoacetic acid tert-butyl ester;
With
zinc;
In
tetrahydrofuran;
at 20 ℃;
for 0.166667h;
Inert atmosphere;
Sealed tube;
2-bromoanisole;
With
monophosphine 1,2,3,4,5-pentaphenyl-1'-(di-tert-butylphosphino)ferrocene; bis(dibenzylideneacetone)-palladium(0);
In
tetrahydrofuran;
at 20 ℃;
for 4h;
Inert atmosphere;
Sealed tube;
DOI:10.1021/jo401476f
- Guidance literature:
-
With
monophosphine 1,2,3,4,5-pentaphenyl-1'-(di-tert-butylphosphino)ferrocene; bis(dibenzylideneacetone)-palladium(0);
In
tetrahydrofuran;
at 20 ℃;
for 4h;
Inert atmosphere;
Sealed tube;
DOI:10.1021/jo401476f
- Guidance literature:
-
acetic acid tert-butyl ester;
With
lithium hexamethyldisilazane;
In
toluene;
at -78 ℃;
for 1h;
Inert atmosphere;
Sealed tube;
With
zinc(II) chloride;
In
tetrahydrofuran; toluene;
at -78 ℃;
for 0.5h;
Inert atmosphere;
Sealed tube;
2-bromoanisole;
With
monophosphine 1,2,3,4,5-pentaphenyl-1'-(di-tert-butylphosphino)ferrocene; bis(dibenzylideneacetone)-palladium(0);
In
tetrahydrofuran; toluene;
at 20 ℃;
for 4h;
Inert atmosphere;
Sealed tube;
DOI:10.1021/jo401476f
