2-Chloro-6-(4-methylphenyl)pyrazine

Base Information

Chemical Name:2-Chloro-6-(4-methylphenyl)pyrazine
CAS No.:637352-85-3
Molecular Formula:C11H9ClN2
Molecular Weight:204.659
Hs Code.:2933990090
DSSTox Substance ID:DTXSID00593886
Nikkaji Number:J2.403.851C
Wikidata:Q82488518
Mol file:637352-85-3.mol

Synonyms:637352-85-3;2-Chloro-6-(p-tolyl)pyrazine;2-Chloro-6-(4-methylphenyl)pyrazine;2-chloro-6-p-tolylpyrazine;SCHEMBL4901225;DTXSID00593886;SPNHICMLNGTAFL-UHFFFAOYSA-N;AKOS014986822;DA-26438;J-508988

Suppliers and Price of 2-Chloro-6-(4-methylphenyl)pyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Chloro-6-(p-tolyl)pyrazine 95+%
1g
$ 535.00

Chemenu
2-chloro-6-(p-tolyl)pyrazine 95%
1g
$ 505.00

American Custom Chemicals Corporation
2-CHLORO-6-(4-METHYLPHENYL)PYRAZINE 95.00%
5MG
$ 505.70

Alichem
2-Chloro-6-(p-tolyl)pyrazine
1g
$ 457.80

Total 10 raw suppliers

Chemical Property of 2-Chloro-6-(4-methylphenyl)pyrazine

Chemical Property:

Melting Point:72.5-73.7 °C
Boiling Point:313.0±37.0 °C(Predicted)
PKA:-1.31±0.10(Predicted)
PSA：25.78000
Density:1.208±0.06 g/cm3(Predicted)
LogP:3.10540
Storage Temp.:2-8°C
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:204.0454260
Heavy Atom Count:14
Complexity:178

Purity/Quality:

98%min ^*data from raw suppliers

2-Chloro-6-(p-tolyl)pyrazine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=CN=CC(=N2)Cl

Technology Process of 2-Chloro-6-(4-methylphenyl)pyrazine

There total 2 articles about 2-Chloro-6-(4-methylphenyl)pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 922524-99-0
2-p-tolylpyrazine 1-oxide

: 637352-85-3
2-chloro-6-p-tolylpyrazine

Guidance literature:: With trichlorophosphate; In N,N-dimethyl-formamide; toluene; at 20 ℃; for 20h;
DOI:10.1002/anie.200602773

Reference yield:

: 4774-14-5
2,6-dichloropyrazine

: 5720-05-8
4-methylphenylboronic acid

: 637352-85-3
2-chloro-6-p-tolylpyrazine

Guidance literature:: With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; water; for 18h; Heating / reflux;