1,2-Cyclopentanediamine

Base Information

• Chemical Name: 1,2-Cyclopentanediamine
• CAS No.: 41330-23-8
• Molecular Formula: C₅H₁₂N₂
• Molecular Weight: 100.164
• Hs Code.: 2925190090
• Mol file: 41330-23-8.mol

Synonyms:(+-)-trans-Cyclopentan-1,2-diyldiamin;(+-)-trans-cyclopentane-1,2-diyldiamine;

Chemical Property of 1,2-Cyclopentanediamine

Chemical Property:

• Vapor Pressure: 1.91mmHg at 25°C
• Refractive Index: 1.492
• Boiling Point: 165.1 °C at 760 mmHg
• Flash Point: 60.2 °C
• PSA: 52.04000
• Density: 0.964 g/cm³
• LogP: 1.22550
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

98%,99%, ^*data from raw suppliers

Cyclopentane-1,2-diamine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2-Cyclopentanediamine

There total 11 articles about 1,2-Cyclopentanediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(+/-)-trans-1,2-diazido-cyclopentane → trans-cyclopentane-1,2-diamine (3145-88-8,40535-43-1,40535-44-2,40535-45-3,41330-23-8,77255-03-9)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃; for 6h;

DOI:10.1016/S0040-4020(01)01198-X

Reference yield: 79.6%

trans-1,2-dibromocyclopentane (10230-26-9) → trans-cyclopentane-1,2-diamine (3145-88-8,40535-43-1,40535-44-2,40535-45-3,41330-23-8,77255-03-9)

Guidance literature:

With ammonia; In ethanol; at 40 - 60 ℃;

Reference yield:

cyclopentene (142-29-0) → trans-cyclopentane-1,2-diamine (3145-88-8,40535-43-1,40535-44-2,40535-45-3,41330-23-8,77255-03-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 8 percent / NaN₃; KMnO₄ / methanol / 4 h

2: 73 percent / H₂ / 10 percent Pd/C / 24 h / 2327.17 Torr

With potassium permanganate; sodium azide; hydrogen; palladium on activated charcoal; In methanol;

DOI:10.1016/S0957-4166(02)00757-7

upstream raw materials:

cyclopentene

cyclopentane-1,2-dione dioxime

trans-cyclopentane-1,2-diol

trans-1,2-dibromocyclopentane

Downstream raw materials:

1,2-trans-diaminocyclopentane diiodoplatinum(II)

(1R*,2R*)-2-aminocyclopentylcarbamic acid tert-butyl ester

2,3-Dimethyl-6,7-dihydro-5H-cyclopentapyrazin

tert-butyl rac-trans-(2-aminocyclopentyl)carbamate

Refernces

• 1、 -. "A method for the treatment of tumor cell proliferative diseases of platinum (II) compound". . . Retrieved 2018/01/11.
• 2、 -. "PLATINUM COMPOUND HAVING AMINO OR ALKYLAMINO-CONTAINING SUCCINIC ACID DERIVATIVES AS LEAVING GROUP, PREPARTION METHOD THEREOF, AND USE THEREOF". . . Retrieved 2014/12/09.