Dipropylglycine

Base Information

• Chemical Name: Dipropylglycine
• CAS No.: 2566-31-6
• Molecular Formula: C8H17NO2
• Molecular Weight: 159.228
• Hs Code.: 2922499990
• NSC Number: 44104
• DSSTox Substance ID: DTXSID80180359
• Nikkaji Number: J554.043G
• Mol file: 2566-31-6.mol

Synonyms:2-amino-2-propylpentanoic acid;alpha,alpha-di-n-propylglycine;dipropylglycine

Chemical Property of Dipropylglycine

Chemical Property:

• Vapor Pressure: 0.00356mmHg at 25°C
• Melting Point: >300 °C
• Refractive Index: 1.467
• Boiling Point: 260.9 °C at 760 mmHg
• PKA: 2.58±0.40(Predicted)
• Flash Point: 111.6 °C
• PSA: 63.32000
• Density: 1.001 g/cm³
• LogP: 2.06900
• Storage Temp.: Store at RT.
• XLogP3: -1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 159.125928785
• Heavy Atom Count: 11
• Complexity: 128

Purity/Quality:

98.5% ^*data from raw suppliers

Di-n-propylglycine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC(CCC)(C(=O)O)N

Technology Process of Dipropylglycine

There total 4 articles about Dipropylglycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5,5-dipropylimidazolidine-2,4-dione (36033-33-7) → 2-amino-2-n-propylvaleric acid (2566-31-6)

Guidance literature:

(hydrolysis);

DOI:10.1021/jm00273a004

Reference yield:

dipropyl-malonic acid monoamide (87113-24-4) → 2-amino-2-n-propylvaleric acid (2566-31-6)

Guidance literature:

With sodium hypobromide; chloroform; at -10 ℃;

Reference yield:

4-heptanone (123-19-3) + potassium cyanide (151-50-8) → 2-amino-2-n-propylvaleric acid (2566-31-6)

Guidance literature:

With methanol; ammonium chloride; at 60 - 70 ℃; Verseifung des Reaktionsprodukts mit konz. wss. HCl;

upstream raw materials:

4-heptanone

potassium cyanide

2-amino-2-propyl-valeric acid ethyl ester

dipropyl-malonic acid monoamide

Downstream raw materials:

N-benzyloxycarbonyldipropylglycine

Refernces