N-Methyl-N-2-propynyl-2-pentanamine hydrochloride

Base Information

• Chemical Name: N-Methyl-N-2-propynyl-2-pentanamine hydrochloride
• CAS No.: 143347-18-6
• Molecular Formula: C₉H₁₇N*ClH
• Molecular Weight: 175.702
• DSSTox Substance ID: DTXSID50931830
• Mol file: 143347-18-6.mol

Synonyms:143347-18-6;N-Methyl-N-2-propynyl-2-pentanamine hydrochloride;N-(2-Pentyl)-N-methylpropargylamine hydrochloride;2-Pentanamine, N-methyl-N-2-propynyl-, hydrochloride;N-methyl-N-prop-2-ynyl-pentan-2-amine hydrochloride;N-methyl-N-prop-2-ynylpentan-2-amine;hydrochloride;SCHEMBL5617543;DTXSID50931830;LS-101537;Z4989743553;N-Methyl-N-(prop-2-yn-1-yl)pentan-2-amine--hydrogen chloride (1/1)

Chemical Property of N-Methyl-N-2-propynyl-2-pentanamine hydrochloride

Chemical Property:

• Vapor Pressure: 1.09mmHg at 25°C
• Boiling Point: 176.5°Cat760mmHg
• Flash Point: 53.1°C
• PSA: 3.24000
• Density: g/cm³
• LogP: 2.54200
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 175.1127773
• Heavy Atom Count: 11
• Complexity: 120

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC(C)N(C)CC#C.Cl

Technology Process of N-Methyl-N-2-propynyl-2-pentanamine hydrochloride

There total 3 articles about N-Methyl-N-2-propynyl-2-pentanamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + N-(2-pentyl)propargylamine hydrochloride → N-(2-pentyl)-N-methylpropargylamine hydrochloride (143347-18-6)

Guidance literature:

With sodium dihydrogenphosphate; In water; at 20 ℃; for 24h; pH=6;

DOI:10.1080/00397910008086975

Reference yield:

2-pentylamine (625-30-9) → N-(2-pentyl)-N-methylpropargylamine hydrochloride (143347-18-6)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol

2: 96 percent / NaH₂PO₄ / H₂O / 24 h / 20 °C / pH 6

With sodium dihydrogenphosphate; In ethanol; water; 1: Alkylation / 2: reductive methylation;

DOI:10.1080/00397910008086975

Reference yield:

→ N-(2-pentyl)-N-methylpropargylamine hydrochloride (143347-18-6)

Guidance literature:

upstream raw materials:

formaldehyd

2-pentylamine