2-mercaptosuccinic acid diethyl ester

Base Information

• Chemical Name: 2-mercaptosuccinic acid diethyl ester
• CAS No.: 23060-14-2
• Molecular Formula: C8H14 O4 S
• Molecular Weight: 206.263
• Hs Code.: 2930909090
• Mol file: 23060-14-2.mol

Synonyms:Butanedioicacid, mercapto-, diethyl ester (9CI); Succinic acid, mercapto-, diethyl ester(6CI,8CI); 2-Mercaptosuccinic acid diethyl ester; Diethyl 2-mercaptosuccinate;Diethyl 2-thiosuccinate; Diethyl mercaptosuccinate; Ethyl mercaptosuccinate

Chemical Property of 2-mercaptosuccinic acid diethyl ester

Chemical Property:

• PSA: 91.40000
• LogP: 0.80110
• Storage Temp.: Refrigerator, Under inert atmosphere
• Solubility.: Chloroform (Sparingly), Methanol (Slightly)

Purity/Quality:

99%min ^*data from raw suppliers

2-Mercapto-succinicAciddiethylester ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-mercaptosuccinic acid diethyl ester

There total 6 articles about 2-mercaptosuccinic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

DL-thiomalic acid (70-49-5,644-87-1) + ethanol (64-17-5) → diethyl 2-mercaptosuccinate (23060-14-2)

Guidance literature:

With toluene-4-sulfonic acid; In chloroform; esterified azeotropically;

Reference yield:

malaoxon (1634-78-2,35805-20-0,145307-18-2,145307-19-3) → dimethylphosphoric acid (813-78-5) + diethyl 2-mercaptosuccinate (23060-14-2)

Guidance literature:

With 5-(hydroxyamino)-5-oxopentanoic acid; In aq. phosphate buffer; at 23 ℃; for 2h; Reagent/catalyst;

DOI:10.1039/c9ob00503j

Reference yield:

diethyl Fumarate (623-91-6) → diethyl 2-mercaptosuccinate (23060-14-2)

Guidance literature:

With pyridine; hydrogen sulfide; unter gleichzeitigem Einleiten von Schwefelwasserstoff;

upstream raw materials:

DL-thiomalic acid

ethanol

diethyl Fumarate

tetrahydropyran-2-ylsulfanyl-succinic acid diethyl ester

Downstream raw materials:

2-[2-(4-Methoxy-phenoxy)-ethylsulfanyl]-succinic acid diethyl ester

2-[2-(4-Chloro-3,5-dimethyl-phenoxy)-ethylsulfanyl]-succinic acid diethyl ester

(Z)-(5-ethoxycarbonylmethyl-4-oxothiazolidin-2-ylidene)-N-phenylethanamide

3-thia-pentane-1,2,4,5-tetracarboxylic acid tetraethyl ester

Refernces

• 1、 -. "Process for Preparing Malathion for Pharmaceutical Use". Page/Page column 13. . Retrieved 2008/06/13.
• 2、 Missakian,Ketcham,Martin. "Chemistry of 2 tetrahydropyranthiol". . p. 2010 - 2012. Retrieved 2007/10/05.